Description

tert-Butyl 2-Benzyl-2,6-Diazaspiro[3.4]Octane-6-Carboxylate is a high-purity, advanced pharmaceutical intermediate featuring a unique spirocyclic scaffold. This compound is of significant value in medicinal chemistry for its role as a key building block in the synthesis of novel drug candidates. It is primarily sought after by research organizations and pharmaceutical companies engaged in the development of new therapeutic agents, particularly within central nervous system (CNS) and oncology research pipelines. The compound's defined structure enables precise molecular modifications critical for early-stage drug discovery and optimization.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the multi-step synthesis of potential active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Used as a versatile scaffold for constructing compound libraries in high-throughput screening (HTS) campaigns.
• Drug Discovery & Development: Integral to structure-activity relationship (SAR) studies for optimizing pharmacokinetic and pharmacodynamic properties.
• Proteolysis Targeting Chimera (PROTAC) Synthesis: Employed in the construction of linkers or warhead components for targeted protein degradation platforms.
• Chemical Biology Probes: Utilized to develop tool compounds for investigating biological pathways and target validation.
• Contract Research & Manufacturing (CRO/CMO): Supplied to service organizations supporting pharmaceutical R&D programs requiring specialized intermediates.

Basic Information

Product Name	tert-Butyl 2-Benzyl-2,6-Diazaspiro[3.4]Octane-6-Carboxylate
CAS No.	1202179-27-8
Molecular Formula	C18H26N2O2
Molecular Weight	302.41 g/mol
Synonyms	2,6-Diazaspiro[3.4]octane-6-carboxylic acid, 2-(phenylmethyl)-, 1,1-dimethylethyl ester; 6-Boc-2-benzyl-2,6-diazaspiro[3.4]octane; tert-Butyl 2-benzyl-2,6-diazaspiro[3.4]octane-6-carboxylate; 2-Benzyl-2,6-diazaspiro[3.4]octane-6-carboxylic acid tert-butyl ester; 2,6-Diazaspiro[3.4]octane, 6-(tert-butoxycarbonyl)-2-benzyl-; Boc-2-Bn-2,6-diazaspiro[3.4]octane
EINECS	Contact for details

Quality Control

Our tert-Butyl 2-Benzyl-2,6-Diazaspiro[3.4]Octane-6-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP guidelines for pharmaceutical intermediates, ensuring traceability and reliability for your research and development needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) in the original sealed container to prevent degradation. Allow the container to reach room temperature before opening to minimize moisture ingress.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.