Description

Ethyl 4-Chloro-7,8-Dihydro-1,6-Naphthyridine-6(5H)-Carboxylate is a high-value, heterocyclic organic building block with significant synthetic utility. This compound serves as a critical intermediate in the development of novel active pharmaceutical ingredients (APIs) and fine chemicals. It is primarily sought after by research and development teams in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly those targeting central nervous system (CNS) disorders, oncology, and infectious diseases.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging the naphthyridine core's bioactivity.
• Organic Synthesis Building Block: The reactive chloro and ester functional groups make it a versatile scaffold for constructing more complex heterocyclic compounds via cross-coupling, hydrolysis, and amidation reactions.
• Material Science Research: Investigated as a monomer or precursor for creating novel organic electronic materials or metal-organic frameworks (MOFs).
• Contract Research & Development (CRO/CMO): Supplied to organizations engaged in custom synthesis and process development for client projects.

Basic Information

Product Name	Ethyl 4-Chloro-7,8-Dihydro-1,6-Naphthyridine-6(5H)-Carboxylate
CAS No.	1201845-49-9
Molecular Formula	C11H13ClN2O2
Molecular Weight	240.69 g/mol
Synonyms	Ethyl 4-chloro-5,6,7,8-tetrahydro-1,6-naphthyridine-6-carboxylate; 4-Chloro-7,8-dihydro-1,6-naphthyridine-6(5H)-carboxylic acid ethyl ester; 6-Carbethoxy-4-chloro-5,6,7,8-tetrahydro-1,6-naphthyridine; 4-Chloro-5,6,7,8-tetrahydro-1,6-naphthyridine-6-carboxylic Acid Ethyl Ester; 1201845-49-9; 4-Chloro-7,8-dihydro-5H-1,6-naphthyridine-6-carboxylic acid ethyl ester
EINECS	Contact for details

Quality Control

Our Ethyl 4-Chloro-7,8-Dihydro-1,6-Naphthyridine-6(5H)-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistent chemical identity. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.