Description

1-Benzyl-5-Chloro-1,2,3,4-Tetrahydro-1,6-Naphthyridine is a high-purity, advanced pharmaceutical intermediate belonging to the naphthyridine class of heterocyclic compounds. This compound is critical for the research and development of novel therapeutic agents, particularly in the fields of oncology and central nervous system (CNS) disorders. It is primarily utilized by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers requiring a reliable and consistent supply of complex building blocks for drug synthesis.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of potential drug candidates targeting various disease pathways.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new chemical entities.
• API Development: Serves as a precursor in the development of Active Pharmaceutical Ingredients (APIs) with naphthyridine-based structures.
• Biochemical Research: Employed as a research tool to study enzyme inhibition and receptor binding activities.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.
• Library Synthesis: Used for the creation of diverse compound libraries for high-throughput screening in drug discovery.

Basic Information

Product Name	1-Benzyl-5-Chloro-1,2,3,4-Tetrahydro-1,6-Naphthyridine
CAS No.	1201785-17-2
Molecular Formula	C₁₉H₁₉ClN₂
Molecular Weight	310.82 g/mol
Synonyms	1-Benzyl-5-chloro-1,2,3,4-tetrahydro-1,6-naphthyridine; 5-Chloro-1-benzyl-1,2,3,4-tetrahydro-1,6-naphthyridine; 1,6-Naphthyridine, 1-benzyl-5-chloro-1,2,3,4-tetrahydro-; 1201785-17-2; 1-Benzyl-5-chloro-1,6-naphthyridine (partial name); BCTN (abbreviation); Tetrahydro-1,6-naphthyridine derivative
EINECS	Contact for details

Quality Control

Our 1-Benzyl-5-Chloro-1,2,3,4-Tetrahydro-1,6-Naphthyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical research. A comprehensive Certificate of Analysis (COA) detailing purity, residual solvents, and related substances is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider inert atmosphere conditions to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.