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5-Bromoquinazolin-4-Amine CAS NO 1201784-87-3
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CAS No.:1201784-87-3
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
5-Bromoquinazolin-4-Amine CAS NO 1201784-87-3 is a high-purity, versatile brominated quinazoline derivative that serves as a critical building block in advanced organic synthesis. Its primary value lies in its functionalized amine and halogen groups, which enable precise molecular modifications for creating novel compounds. This intermediate is essential for researchers and process chemists in the pharmaceutical and agrochemical industries, particularly for developing targeted small-molecule libraries and active ingredients.
Application
- Pharmaceutical Intermediate: A key precursor in the synthesis of kinase inhibitors and other biologically active quinazoline-based compounds for oncology and other therapeutic areas.
- Agrochemical Research: Used in the development of novel herbicides and fungicides, leveraging the quinazoline scaffold for bioactivity.
- Material Science: Serves as a monomer or functional additive in the creation of specialty polymers and advanced organic electronic materials.
- Chemical Synthesis: An important reagent for cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and nucleophilic substitution, facilitating complex molecule construction.
- Academic & R&D: Employed in university and corporate research laboratories for methodological studies and the discovery of new chemical entities.
Basic Information
| Product Name | 5-Bromoquinazolin-4-Amine |
| CAS No. | 1201784-87-3 |
| Molecular Formula | C8H6BrN3 |
| Molecular Weight | 224.06 g/mol |
| Synonyms | 4-Amino-5-bromoquinazoline; 5-Bromo-4-quinazolinamine; 5-Bromoquinazolin-4-ylamine; Quinazoline, 5-bromo-4-amino-; 1201784-87-3; 5-Br-QA |
| EINECS | Contact for details |
Quality Control
Our 5-Bromoquinazolin-4-Amine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment and is available upon request.
Storage
Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong alkalis and incompatible organic solvents. The compound is light-sensitive and should be handled accordingly to maintain stability.
Specification
| Item | Specification |
|---|---|
| Appearance | Off-white to light yellow crystalline powder |
| Identification (IR) | Conforms to structure |
| Identification (HPLC) | Conforms to reference |
| Purity (HPLC) | ≥ 98.0% |
| Loss on Drying | ≤ 0.5% |
| Residue on Ignition | ≤ 0.1% |
| Heavy Metals | ≤ 20 ppm |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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