Description

4-(3-Acetyl-8-Bromo-3H-Pyrazolo[3,4-C]Quinolin-1-Yl)-Alpha,α-Dimethylbenzeneacetonitrile is a high-value, complex heterocyclic building block and advanced pharmaceutical intermediate. This compound is critical for research and development in medicinal chemistry, particularly for synthesizing novel drug candidates targeting various therapeutic areas. It is primarily sought after by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers engaged in the synthesis of complex molecules.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), especially in oncology and CNS drug discovery.
• Medicinal Chemistry Research: Used as a sophisticated scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• Chemical Biology Probe Development: Employed in the design and synthesis of molecular probes to study biological pathways and protein functions.
• Fine Chemical Synthesis: Acts as a specialized building block for the multi-step synthesis of complex heterocyclic compounds in custom manufacturing.
• Academic Research: Utilized in university and institutional labs for advanced organic synthesis methodology development and novel compound exploration.

Basic Information

Product Name	4-(3-Acetyl-8-Bromo-3H-Pyrazolo[3,4-C]Quinolin-1-Yl)-Alpha,α-Dimethylbenzeneacetonitrile
CAS No.	1201643-72-2
Molecular Formula	C24H19BrN4O
Molecular Weight	459.34 g/mol
Synonyms	4-(3-Acetyl-8-bromo-3H-pyrazolo[3,4-c]quinolin-1-yl)-α,α-dimethylbenzeneacetonitrile; 4-(3-Acetyl-8-bromo-3H-pyrazolo[3,4-c]quinolin-1-yl)-2-methyl-2-phenylpropionitrile; 1-(2-Cyano-2-methyl-2-phenylethyl)-3-acetyl-8-bromo-3H-pyrazolo[3,4-c]quinoline; 8-Bromo-3-acetyl-1-(2-cyano-2-methyl-2-phenylethyl)-3H-pyrazolo[3,4-c]quinoline; 1201643-72-2; Pyrazoloquinoline derivative; Brominated pyrazoloquinoline intermediate
EINECS	Contact for details

Quality Control

Our 4-(3-Acetyl-8-Bromo-3H-Pyrazolo[3,4-C]Quinolin-1-Yl)-Alpha,α-Dimethylbenzeneacetonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.