Description

n-Tosyl-5-Bromo-4,7-Diazaindole is a high-purity, advanced pharmaceutical intermediate characterized by its unique heterocyclic structure. This compound is essential for the synthesis of complex molecules, particularly in medicinal chemistry and drug discovery programs. It is primarily utilized by research institutions and pharmaceutical companies developing novel therapeutic agents, especially kinase inhibitors and other targeted small-molecule drugs.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs) for preclinical and clinical research.
• Medicinal Chemistry: Used in structure-activity relationship (SAR) studies and the development of novel drug candidates, particularly kinase inhibitors.
• Biochemical Research: Serves as a precursor or reference standard in biochemical assays and proteomics research.
• Organic Synthesis: Employed in academic and industrial laboratories for constructing complex nitrogen-containing heterocycles.
• Chemical Biology: Useful for developing chemical probes to study biological pathways and protein functions.

Basic Information

Item	Details
Product Name	n-Tosyl-5-Bromo-4,7-Diazaindole
CAS No.	1201186-54-0
Molecular Formula	C14H10BrN3O2S
Molecular Weight	364.22 g/mol
Synonyms	5-Bromo-1-(4-methylphenyl)sulfonyl-1H-pyrrolo[2,3-b]pyridine; 5-Bromo-1-tosyl-1H-pyrrolo[2,3-b]pyridine; 5-Bromo-1H-pyrrolo[2,3-b]pyridine, 1-[(4-methylphenyl)sulfonyl]-; 1-Tosyl-5-bromo-1H-pyrrolo[2,3-b]pyridine; 5-Bromo-1-(p-tolylsulfonyl)-1H-pyrrolo[2,3-b]pyridine; 5-Bromo-4,7-diazaindole N-tosyl derivative
EINECS	Contact for details

Quality Control

Our n-Tosyl-5-Bromo-4,7-Diazaindole is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all specification results. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.