Description

5,7-Difluoro-1,2,3,4-Tetrahydro-Naphthalen-1-Ylamine Hydrochloride is a high-purity fluorinated amine hydrochloride salt, serving as a critical building block in advanced organic synthesis. Its value lies in providing a functionalized, conformationally constrained tetralin scaffold that is essential for developing novel bioactive molecules. This compound is primarily needed by research institutions and pharmaceutical companies engaged in medicinal chemistry, particularly for the discovery and development of new therapeutic agents targeting the central nervous system and other disease areas.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new drug candidates, especially in neuroscience and oncology.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to explore and optimize the biological activity of tetralin-based compounds.
• Ligand and Probe Synthesis: Serves as a precursor for creating specialized chemical probes and ligands for biological target validation.
• Agrochemical Development: Potential intermediate in the synthesis of novel fluorinated active ingredients for crop protection.
• Academic Research: Employed in universities and research institutes for methodological studies in fluorination and asymmetric synthesis.
• Material Science Precursor: Can be utilized in the development of advanced organic materials and specialty chemicals.

Basic Information

Product Name	5,7-Difluoro-1,2,3,4-Tetrahydro-Naphthalen-1-Ylamine Hydrochloride
CAS No.	1199783-14-6
Molecular Formula	C₁₀H₁₂ClF₂N
Molecular Weight	219.66 g/mol
Synonyms	1-Amino-5,7-difluoro-1,2,3,4-tetrahydronaphthalene hydrochloride; 5,7-Difluoro-1,2,3,4-tetrahydro-1-naphthalenamine hydrochloride; 1,2,3,4-Tetrahydro-5,7-difluoro-1-naphthylamine hydrochloride; 5,7-Difluoro-1-tetralinamine hydrochloride; 5,7-Difluoro-1-amino-1,2,3,4-tetrahydronaphthalene HCl; 5,7-Difluoro-1,2,3,4-tetrahydro-1-naphthylamine HCl; 5,7-Difluoro-1,2,3,4-tetrahydro-naphthalen-1-ylamine hydrochloride
EINECS	Contact for details

Quality Control

Our 5,7-Difluoro-1,2,3,4-Tetrahydro-Naphthalen-1-Ylamine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical research and development. Certificates of Analysis (COA) with detailed chromatographic data are available upon request to support your regulatory and quality assurance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Chiral Purity (Chiral HPLC)	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.