Description

2-Bromo-4-Chloro-n-Methylaniline Hydrochloride is a high-purity, halogenated aniline derivative salt, serving as a critical building block in advanced organic synthesis. Its value lies in providing a functionalized aromatic amine core that is essential for constructing complex molecular architectures. This intermediate is particularly vital for research and development chemists in the pharmaceutical and agrochemical industries, where it is used to create novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Synthesis: Used in the development of new herbicides, fungicides, and insecticides, leveraging its halogenated structure for bioactivity.
• Dye and Pigment Manufacturing: Serves as a foundational component for producing specialized azo dyes and high-performance pigments.
• Material Science Research: Employed in the creation of organic electronic materials, such as charge-transport layers and photoactive compounds.
• Cross-Coupling Reactions: Acts as a substrate in Buchwald-Hartwig amination and other palladium-catalyzed coupling reactions to form carbon-nitrogen bonds.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for bespoke synthesis projects and scale-up processes.

Basic Information

Product Name	2-Bromo-4-Chloro-n-Methylaniline Hydrochloride
CAS No.	1199773-47-1
Molecular Formula	C7H8BrClN • HCl
Molecular Weight	266.96 g/mol (Free base: 220.50 g/mol)
Synonyms	2-Bromo-4-chloro-N-methylaniline hydrochloride; 1-Amino-2-bromo-4-chloro-N-methylbenzene hydrochloride; N-Methyl-2-bromo-4-chloroaniline hydrochloride; Benzenamine, 2-bromo-4-chloro-N-methyl-, hydrochloride; 2-Bromo-4-chloro-N-methylbenzenamine hydrochloride
EINECS	Contact for details

Quality Control

Our 2-Bromo-4-Chloro-n-Methylaniline Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, detailing compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept sealed under dry conditions to prevent moisture absorption, which can affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.