Description

3,5-Di(1H-Imidazol-1-Yl)Benzoic Acid is a high-purity, multi-functional organic building block featuring a benzoic acid core symmetrically substituted with two imidazole rings. This unique molecular architecture makes it a versatile intermediate for synthesizing advanced materials and pharmaceutical candidates, particularly those requiring metal coordination or hydrogen bonding sites. It is primarily utilized by research institutions and industrial R&D departments in medicinal chemistry, materials science, and as a precursor for specialized ligands.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the development of novel active pharmaceutical ingredients (APIs), especially for targets involving imidazole-based pharmacophores.
• Metal-Organic Framework (MOF) Synthesis: Acts as a multi-dentate organic linker for constructing porous coordination polymers with potential applications in gas storage, separation, and catalysis.
• Ligand for Catalysis: Used to prepare N-donor ligands for transition metal catalysts in organic synthesis and polymerization reactions.
• Functional Material Development: Incorporated into polymers and coatings to impart specific chemical or electronic properties.
• Biochemical Research: Employed in the study of enzyme inhibition and protein-ligand interactions due to its ability to mimic histidine residues.
• Academic & Industrial R&D: A valuable compound for exploratory synthesis in chemical research and development projects.

Basic Information

Product Name	3,5-Di(1H-Imidazol-1-Yl)Benzoic Acid
CAS No.	1199574-21-4
Molecular Formula	C14H10N4O2
Molecular Weight	266.26 g/mol
Synonyms	3,5-Bis(1H-imidazol-1-yl)benzoic acid; 3,5-Di(imidazol-1-yl)benzoic acid; Benzoic acid, 3,5-bis(1H-imidazol-1-yl)-; 1,1'-(5-Carboxy-1,3-phenylene)diimidazole; 3,5-Diimidazol-1-yl-benzoic acid; AI3-52362; BDBM50150085; ZINC000003869756
EINECS	Contact for details

Quality Control

Our 3,5-Di(1H-Imidazol-1-Yl)Benzoic Acid is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are available upon request. We support custom synthesis and purity grades to meet specific research or project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). The compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if specified for long-term storage.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.