Description

3-(4-Fluorophenyl)Pyrrolidine: Oxalic Acid is a high-purity, non-racemic salt form of a fluorinated pyrrolidine derivative, offering a stable and well-defined chemical entity for advanced synthesis. This compound is critical for pharmaceutical research and development, particularly in the creation of novel active pharmaceutical ingredients (APIs) and chiral intermediates. It is primarily utilized by medicinal chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries seeking to incorporate a fluorinated, conformationally constrained amine moiety into complex molecular architectures.

Application

• Pharmaceutical Intermediate: Serves as a key chiral building block in the synthesis of potential drug candidates, especially for central nervous system (CNS) targets and kinase inhibitors.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides where the fluorophenyl-pyrrolidine scaffold can impart specific biological activity.
• Ligand and Catalyst Development: Acts as a precursor for chiral ligands used in asymmetric catalysis, enabling the synthesis of enantiomerically pure compounds.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying enzyme function and receptor interactions.
• Material Science Research: Investigated as a monomer or functional additive for creating specialty polymers with unique optical or electronic properties.

Basic Information

Product Name	3-(4-Fluorophenyl)Pyrrolidine: Oxalic Acid
CAS No.	1198416-84-0
Molecular Formula	C12H14FNO4
Molecular Weight	255.24 g/mol
Synonyms	3-(4-Fluorophenyl)pyrrolidine oxalate; (S)-3-(4-Fluorophenyl)pyrrolidine oxalic acid salt; 3-(p-Fluorophenyl)pyrrolidine hydrogen oxalate; 1-(4-Fluorophenyl)-3-pyrrolidinol oxalate (tautomer); 4-Fluoro-β-(2-pyrrolidinyl)benzenemethanol oxalate; Pyrrolidine, 3-(4-fluorophenyl)-, (3S)-, ethanedioate (1:1); FPP-Oxalate
EINECS	Contact for details

Quality Control

Our 3-(4-Fluorophenyl)Pyrrolidine: Oxalic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity assessment by HPLC, to ensure it meets the high standards required for research and development. A Certificate of Analysis (COA) detailing identity, purity, chiral excess, and impurity profiles is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which may affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% e.e.
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Maximum Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.