Description

4-Bromo-2-Fluoro-n-Methylaniline Hcl is a high-purity halogenated aniline derivative, serving as a critical building block in advanced organic synthesis. Its value lies in providing a functionalized aromatic scaffold with multiple reactive sites, enabling the construction of complex molecular architectures. This intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing active ingredients and novel chemical entities.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for compounds targeting central nervous system disorders and other therapeutic areas.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, leveraging its halogenated structure for bioactivity.
• Material Science Research: Serves as a monomer or functionalizing agent in the creation of specialty polymers, liquid crystals, and organic electronic materials.
• Dye and Pigment Manufacturing: Acts as an intermediate for producing complex azo dyes and high-performance pigments.
• Cross-Coupling Reactions: An excellent substrate for palladium-catalyzed reactions like Suzuki, Buchwald-Hartwig, and Ullmann couplings to form new carbon-carbon and carbon-heteroatom bonds.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes and tags for studying biological processes.

Basic Information

Product Name	4-Bromo-2-Fluoro-n-Methylaniline Hcl
CAS No.	1197930-28-1
Molecular Formula	C7H8BrClFN
Molecular Weight	240.50 g/mol
Synonyms	4-Bromo-2-fluoro-N-methylaniline hydrochloride; 1-Bromo-4-fluoro-2-(methylamino)benzene hydrochloride; 2-Fluoro-4-bromo-N-methylaniline HCl; N-Methyl-4-bromo-2-fluoroaniline hydrochloride; Benzenamine, 4-bromo-2-fluoro-N-methyl-, hydrochloride; 4-Bromo-2-fluoro-N-methylbenzenamine hydrochloride
EINECS	Contact for details

Quality Control

Our 4-Bromo-2-Fluoro-n-Methylaniline Hcl is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with agreed specifications. Our quality commitment supports applications requiring high standards, including cGMP intermediates for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥98.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Related Substances (HPLC)	Total impurities ≤2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.