Description

tert-Butyl 2'-tert-Butyl-7'-Oxo-6',7'-Dihydro-2'H-Spiro[Piperidine-4,5'-Pyrano[3,2-C]Pyrazole]-1-Carboxylate is a high-value, complex heterocyclic compound featuring a spirocyclic and fused pyranopyrazole structure. This molecule serves as a critical advanced pharmaceutical intermediate (API intermediate) and a versatile scaffold in medicinal chemistry research. It is primarily sought after by R&D and production teams in the pharmaceutical and biotechnology sectors for the synthesis of novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of potential drug candidates targeting various disease pathways.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery.
• Protease Inhibitor Development: The structural motifs suggest potential application in developing inhibitors for serine or cysteine proteases.
• Kinase Inhibitor Synthesis: Serves as a precursor for compounds designed to modulate kinase activity, relevant in oncology and inflammatory diseases.
• Chemical Biology Probes: Utilized in the creation of molecular probes to study specific biological processes and protein functions.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.

Basic Information

Product Name	tert-Butyl 2'-tert-Butyl-7'-Oxo-6',7'-Dihydro-2'H-Spiro[Piperidine-4,5'-Pyrano[3,2-C]Pyrazole]-1-Carboxylate
CAS No.	1197815-67-0
Molecular Formula	C19H29N3O3
Molecular Weight	347.45 g/mol
Synonyms	1-Boc-2'-tert-butyl-6',7'-dihydro-2'H-spiro[piperidine-4,5'-pyrano[3,2-c]pyrazol]-7'-one; tert-Butyl 2'-tert-butyl-7'-oxo-2',6',7',8'-tetrahydro-1'H,5'H-spiro[piperidine-4,5'-pyrano[3,2-c]pyrazole]-1-carboxylate; 2'-tert-Butyl-7'-oxo-6',7'-dihydro-2'H-spiro[piperidine-4,5'-pyrano[3,2-c]pyrazole]-1-carboxylic acid tert-butyl ester; Spiropyranopyrazole derivative; CAS 1197815-67-0
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with each shipment. We support development under cGMP guidelines as required for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound may be moisture-sensitive; keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.