Description

(1S)-5,5',6,6',7,7',8,8'-Octahydro-3,3'-Bis[2,4,6-Tris(1-Methylethyl)Phenyl]-[1,1'-Binaphthalene]-2,2'-Diol is a sophisticated chiral ligand and catalyst precursor, prized for its sterically demanding and electron-rich structure. This compound matters for enabling highly selective and efficient asymmetric transformations in advanced organic synthesis. It is essential for researchers and process chemists in the pharmaceutical, agrochemical, and fine chemical industries who require precise stereochemical control.

Application

• Asymmetric Catalysis: As a key chiral ligand for transition metals (e.g., Rh, Ru, Pd) in enantioselective hydrogenation, C-C bond formation, and other catalytic reactions.
• Pharmaceutical Intermediate Synthesis: For the production of enantiomerically pure active pharmaceutical ingredients (APIs) where chirality is critical for biological activity.
• Agrochemical Development: In the synthesis of chiral pesticides and herbicides to enhance efficacy and reduce environmental impact.
• Material Science Research: As a building block for chiral polymers, sensors, or advanced functional materials with specific optical properties.
• Methodology Development: Used by academic and industrial R&D laboratories to develop new catalytic systems and synthetic methodologies.
• Fine Chemical Production: For the manufacture of high-value specialty chemicals, flavors, and fragrances requiring enantiopurity.

Basic Information

Product Name	(1S)-5,5',6,6',7,7',8,8'-Octahydro-3,3'-Bis[2,4,6-Tris(1-Methylethyl)Phenyl]-[1,1'-Binaphthalene]-2,2'-Diol
CAS No.	1197214-47-3
Molecular Formula	C52H66O2
Molecular Weight	723.08 g/mol
Synonyms	(S)-H8-BINOL-DTBP; (S)-Octahydro-3,3'-di(2,4,6-triisopropylphenyl)-1,1'-binaphthyl-2,2'-diol; (S)-DTBP-H8-BINOL; (1S)-H8-3,3'-Bis(2,4,6-triisopropylphenyl)-[1,1'-binaphthalene]-2,2'-diol; (S)-5,5',6,6',7,7',8,8'-Octahydro-3,3'-bis(2,4,6-triisopropylphenyl)-2,2'-dihydroxy-1,1'-binaphthyl; Chiral H8-BINOL Derivative; Asymmetric BINOL Ligand
EINECS	Contact for details

Quality Control

Our (1S)-5,5',6,6',7,7',8,8'-Octahydro-3,3'-Bis[2,4,6-Tris(1-Methylethyl)Phenyl]-[1,1'-Binaphthalene]-2,2'-Diol is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis by HPLC, to ensure high chemical and enantiomeric purity suitable for demanding catalytic applications. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept tightly sealed in a dry environment to prevent moisture absorption, which may affect performance. For long-term storage, consider using an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.