Description

4-Ethoxy-2-Fluoro-1-(Phenylmethoxy)Benzene is a high-purity fluorinated aromatic ether building block of significant interest in advanced organic synthesis. Its molecular structure, featuring both ethoxy and benzyloxy protecting groups adjacent to a fluorine atom, makes it a versatile intermediate for constructing complex molecules. This compound is primarily utilized by research institutions and pharmaceutical companies engaged in the development of new active pharmaceutical ingredients (APIs) and specialty fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel drug candidates, particularly in medicinal chemistry programs targeting CNS and anti-inflammatory applications.
• Agrochemical Synthesis: Serves as a precursor in the design and synthesis of new-generation herbicides and pesticides with enhanced efficacy.
• Liquid Crystal Materials: Used in the synthesis of fluorinated components for liquid crystal displays (LCDs) to modify dielectric anisotropy and viscosity.
• Organic Electronics: Acts as a building block for electron-transport materials and semiconductors in OLED and OFET research.
• Complex Ligand Synthesis: Employed in the preparation of specialized ligands for catalysis and metal-organic frameworks (MOFs).
• Academic & Industrial R&D: A valuable reagent for methodological studies in fluorination chemistry and cross-coupling reactions.

Basic Information

Item	Detail
Product Name	4-Ethoxy-2-Fluoro-1-(Phenylmethoxy)Benzene
CAS No.	1196486-65-3
Molecular Formula	C15H15FO2
Molecular Weight	246.28 g/mol
Synonyms	1-(Benzyloxy)-4-ethoxy-2-fluorobenzene; 2-Fluoro-1-(phenylmethoxy)-4-ethoxybenzene; 4-Ethoxy-2-fluorophenyl benzyl ether; Benzene, 1-(benzyloxy)-4-ethoxy-2-fluoro-; 2-Fluoro-4-ethoxyphenyl benzyl ether
EINECS	Contact for details

Quality Control

Our 4-Ethoxy-2-Fluoro-1-(Phenylmethoxy)Benzene is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing including HPLC, GC, NMR, and mass spectrometry to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We support cGMP compliance for pharmaceutical applications and can tailor purity grades to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong oxidizing agents. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0% (Standard Grade)
Purity (GC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.