Description

(3-Fluoro-4-Nitro-Benzyl)-Carbamic Acid tert-Butyl Ester is a high-purity, protected amine derivative serving as a critical building block in advanced organic synthesis. Its value lies in providing a versatile and reactive scaffold for constructing complex molecules, particularly in pharmaceutical research and development. This compound is essential for medicinal chemists and process development scientists working on novel active pharmaceutical ingredients (APIs), agrochemicals, and specialty materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Research: Building block for developing new herbicides, fungicides, and insecticides with enhanced efficacy.
• Peptide Mimetics & PROTACs: Used in the construction of peptide-like molecules and Proteolysis Targeting Chimeras (PROTACs) for targeted protein degradation.
• Ligand & Catalyst Development: Serves as a starting material for creating specialized ligands and organocatalysts used in asymmetric synthesis.
• Material Science: Intermediate for synthesizing specialty polymers and advanced organic electronic materials.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthesis projects.

Basic Information

Product Name	(3-Fluoro-4-Nitro-Benzyl)-Carbamic Acid tert-Butyl Ester
CAS No.	1196157-39-7
Molecular Formula	C₁₂H₁₅FN₂O₄
Molecular Weight	270.26 g/mol
Synonyms	tert-Butyl N-[(3-Fluoro-4-Nitrophenyl)Methyl]Carbamate; N-Boc-3-Fluoro-4-Nitrobenzylamine; Boc-3-Fluoro-4-Nitrobenzylamine; (3-Fluoro-4-Nitrobenzyl)carbamic Acid 1,1-Dimethylethyl Ester; 1,1-Dimethylethyl N-[(3-Fluoro-4-Nitrophenyl)Methyl]Carbamate; N-(tert-Butoxycarbonyl)-3-Fluoro-4-Nitrobenzylamine; Boc-Protected 3-Fluoro-4-Nitrobenzylamine; BOC-(3-Fluoro-4-Nitro-Benzyl)Amine
EINECS	Contact for details

Quality Control

Our (3-Fluoro-4-Nitro-Benzyl)-Carbamic Acid tert-Butyl Ester is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with customer specifications and industry best practices for fine chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat, open flames, and incompatible materials. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC/MS)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.