Description

4-Chloro-6,7-Dihydro-5H-Quinolin-8-One is a high-purity, synthetically valuable heterocyclic building block. This compound is a critical intermediate in the research and development of novel active pharmaceutical ingredients (APIs) and advanced organic materials. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of potential drug candidates, particularly in kinase inhibitor research and other therapeutic areas.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides due to its quinoline-based structure.
• Organic Synthesis Building Block: Serves as a versatile precursor for further functionalization, including cross-coupling reactions and heterocycle formation.
• Material Science Research: Investigated as a component in the development of organic semiconductors, ligands for catalysts, and photoactive materials.
• Chemical Reference Standard: Supplied as a high-purity analytical standard for quality control and method development in analytical laboratories.

Basic Information

Product Name	4-Chloro-6,7-Dihydro-5H-Quinolin-8-One
CAS No.	1196156-61-2
Molecular Formula	C9H8ClNO
Molecular Weight	181.62 g/mol
Synonyms	4-Chloro-5,6,7,8-tetrahydroquinolin-8-one; 8-Quinolinone, 4-chloro-5,6,7,8-tetrahydro-; 4-Chloro-5,6,7,8-tetrahydroquinolin-8(5H)-one; 4-Chloro-6,7-dihydro-8(5H)-quinolinone; 4-Chloro-5,6,7,8-tetrahydro-8-quinolinone
EINECS	Contact for details

Quality Control

Our 4-Chloro-6,7-Dihydro-5H-Quinolin-8-One is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with agreed specifications. We support cGMP standards for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.