Description

5,6,7,8-Tetrahydro-1,7-Naphthyridin-2-Ol is a high-purity, heterocyclic organic compound serving as a critical building block in advanced pharmaceutical research and development. Its unique fused bicyclic structure makes it a valuable intermediate for synthesizing novel drug candidates, particularly in central nervous system (CNS) and oncology therapeutic areas. This compound is essential for medicinal chemists and R&D departments in pharmaceutical companies and contract research organizations (CROs) seeking to develop new active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the development of novel drug molecules, especially for neurological and oncological targets.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Chemical Synthesis: Serves as a building block for constructing more complex heterocyclic compounds and fine chemicals.
• Biochemical Research: Potential use as a ligand or probe in biochemical assays and enzyme inhibition studies.
• Academic Research: Employed in university and institutional labs for fundamental organic chemistry and pharmacology studies.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.

Basic Information

Product Name	5,6,7,8-Tetrahydro-1,7-Naphthyridin-2-Ol
CAS No.	1196154-84-3
Molecular Formula	C8H10N2O
Molecular Weight	150.18 g/mol
Synonyms	5,6,7,8-Tetrahydro-1,7-naphthyridin-2-ol; 2-Hydroxy-5,6,7,8-tetrahydro-1,7-naphthyridine; 1,7-Naphthyridin-2-ol, 5,6,7,8-tetrahydro-; THN-2-ol; 5,6,7,8-Tetrahydro-1,7-naphthyridin-2(1H)-one (tautomer); 2-Oxo-1,2,5,6,7,8-hexahydro-1,7-naphthyridine
EINECS	Contact for details

Quality Control

Our 5,6,7,8-Tetrahydro-1,7-Naphthyridin-2-Ol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our quality commitment aligns with the standards expected for pharmaceutical intermediates in research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.