Description

6-Bromo-2-Oxo-2,3,4,8-Tetrahydro-1,8-Naphthyridine-3-Carboxylic Acid is a high-purity, advanced pharmaceutical intermediate with the CAS number 1196154-23-0. This compound is a critical building block in modern medicinal chemistry, valued for its naphthyridine core which is instrumental in the synthesis of bioactive molecules. It is primarily sought after by research institutions and pharmaceutical companies engaged in the development of novel therapeutic agents, particularly in areas requiring complex heterocyclic scaffolds.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new active pharmaceutical ingredients (APIs), especially those targeting complex diseases.
• Medicinal Chemistry Research: Serves as a versatile scaffold for constructing libraries of compounds in drug discovery programs, particularly for kinase inhibitors or other enzyme-targeted therapies.
• Organic Synthesis Building Block: Used in multi-step synthetic routes to create more complex naphthyridine and fused heterocyclic derivatives.
• Chemical Reference Standard: Employed as an analytical standard in quality control laboratories for method development and validation in pharmaceutical analysis.
• Biochemical Tool Compound: Potential use in biochemical assays to study enzyme interactions and biological pathways due to its specific bromo and carboxylic acid functional groups.

Basic Information

Product Name	6-Bromo-2-Oxo-2,3,4,8-Tetrahydro-1,8-Naphthyridine-3-Carboxylic Acid
CAS No.	1196154-23-0
Molecular Formula	C9H7BrN2O3
Molecular Weight	271.07 g/mol
Synonyms	6-Bromo-1,8-naphthyridine-3-carboxylic acid, 2,3,4,8-tetrahydro-2-oxo-; 6-Bromo-2-oxo-1,2,3,4-tetrahydro-1,8-naphthyridine-3-carboxylic acid; 3-Carboxy-6-bromo-1,2,3,4-tetrahydro-1,8-naphthyridin-2-one; 6-Bromo-2-oxo-2,3,4,8-tetrahydro-1,8-naphthyridine-3-carboxylic acid; 1196154-23-0; 6-Bromo-2-oxo-1,2,3,4-tetrahydro-[1,8]naphthyridine-3-carboxylic acid
EINECS	Contact for details

Quality Control

Our 6-Bromo-2-Oxo-2,3,4,8-Tetrahydro-1,8-Naphthyridine-3-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications and test results are provided and available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. The compound is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.