Description

(5-Fluoro-Pyrimidin-2-Yl)-Acetic Acid CAS NO 1196145-38-6 is a high-purity fluorinated pyrimidine derivative, serving as a critical building block in advanced organic synthesis. Its molecular structure, featuring both a pyrimidine ring and a reactive acetic acid moiety, makes it an invaluable intermediate for constructing complex molecules with tailored properties. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of fluorinated drug candidates, particularly for oncology, antiviral, and CNS-targeted therapies.
• Agrochemical Research: Used to develop novel herbicides, fungicides, and insecticides where the fluorine atom enhances biological activity and metabolic stability.
• Chemical Biology & Proteomics: Serves as a versatile scaffold for creating molecular probes, enzyme inhibitors, and activity-based protein profiling (ABPP) reagents.
• Material Science: Building block for synthesizing specialty polymers, liquid crystals, and organic electronic materials requiring fluorinated heterocycles.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs and fine chemical companies for custom synthesis projects and scale-up development.

Basic Information

Product Name	(5-Fluoro-Pyrimidin-2-Yl)-Acetic Acid
CAS No.	1196145-38-6
Molecular Formula	C6H5FN2O2
Molecular Weight	156.11 g/mol
Synonyms	2-(5-Fluoropyrimidin-2-yl)acetic acid; (5-Fluoropyrimidin-2-yl)acetic Acid; 5-Fluoro-2-pyrimidineacetic Acid; 2-Pyrimidineacetic acid, 5-fluoro-; 1196145-38-6; 5-Fluoropyrimidine-2-acetic acid
EINECS	Contact for details

Quality Control

Our (5-Fluoro-Pyrimidin-2-Yl)-Acetic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.