Description

4-Bromo-7-Fluorobenzofuran is a high-purity, halogenated benzofuran derivative serving as a critical building block in advanced organic synthesis. This compound is valued for its unique molecular scaffold, which enables the introduction of both bromine and fluorine substituents in a fused heterocyclic system, facilitating the development of novel chemical entities. It is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for applications in medicinal chemistry, material science, and as a key intermediate in the synthesis of complex molecules.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used in the creation of novel herbicides, fungicides, and insecticides, leveraging the bioactivity of the halogenated benzofuran core.
• Material Science Research: Serves as a precursor for the synthesis of organic electronic materials, such as OLED (Organic Light-Emitting Diode) emitters and charge-transport materials.
• Medicinal Chemistry: Employed in structure-activity relationship (SAR) studies and lead optimization campaigns to explore new chemical space.
• Chemical Biology Probes: Utilized as a scaffold for developing fluorescent tags or molecular probes for biological imaging and diagnostic applications.
• Cross-Coupling Reactions: The bromine atom makes it an excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Stille) to create more complex biaryl structures.

Basic Information

Product Name	4-Bromo-7-Fluorobenzofuran
CAS No.	1194376-46-9
Molecular Formula	C8H4BrFO
Molecular Weight	215.02 g/mol
Synonyms	7-Fluoro-4-bromobenzofuran; 4-Bromo-7-fluorobenzofuran; Benzofuran, 4-bromo-7-fluoro-; 4-Bromo-7-fluoro-1-benzofuran; 4-Brom-7-fluorbenzofuran (German); 4-ブロモ-7-フルオロベンゾフラン (Japanese)
EINECS	Contact for details

Quality Control

Our 4-Bromo-7-Fluorobenzofuran is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with each shipment to guarantee it meets your specific research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.