Description

tert-Butyl 6-Oxo-2,7-Diazaspiro[4.4]Nonane-2-Carboxylate is a high-value, advanced pharmaceutical intermediate featuring a unique spirocyclic diaza scaffold. This compound is critical for medicinal chemistry research and development, serving as a versatile building block for constructing complex molecular architectures. It is primarily utilized by pharmaceutical and biotechnology companies in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and oncology targets.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, especially those targeting neurological disorders and cancer.
• Medicinal Chemistry Research: Used as a constrained scaffold in structure-activity relationship (SAR) studies and lead optimization programs.
• Proteolysis Targeting Chimera (PROTAC) Development: Serves as a component for constructing linkers or warheads in bifunctional degrader molecules.
• Chemical Biology Probes: Employed in the development of tool compounds for studying enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for the production of bespoke compounds under cGMP or research-grade conditions.
• Academic Research: Utilized in university and institutional labs for exploratory synthetic chemistry and new methodology development.

Basic Information

Item	Detail
Product Name	tert-Butyl 6-Oxo-2,7-Diazaspiro[4.4]Nonane-2-Carboxylate
CAS No.	1194376-44-7
Molecular Formula	C12H20N2O3
Molecular Weight	240.30 g/mol
Synonyms	2,7-Diazaspiro[4.4]nonane-2-carboxylic acid, 6-oxo-, 1,1-dimethylethyl ester; 2-(tert-Butoxycarbonyl)-2,7-diazaspiro[4.4]nonan-6-one; Boc-2,7-diazaspiro[4.4]nonan-6-one; tert-Butyl 6-oxo-2,7-diazaspiro[4.4]nonane-2-carboxylate; 6-Oxo-2,7-diazaspiro[4.4]nonane-2-carboxylic acid tert-butyl ester; 1194376-44-7; Boc-protected 2,7-diazaspiro[4.4]nonan-6-one.
EINECS	Contact for details

Quality Control

Our tert-Butyl 6-Oxo-2,7-Diazaspiro[4.4]Nonane-2-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and consistent identity. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We can supply material suitable for research use or under more stringent controls for advanced development phases.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container sealed to protect from moisture. This material is compatible with strong acids and organic solvents but should be stored separately from incompatible substances.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.