Description

2-Benzyl-2,6-Diazaspiro[3.3]Heptane Hydrochloride is a high-purity, pharmaceutically relevant building block and intermediate, essential for modern drug discovery and development. Its value lies in its unique spirocyclic diaza structure, which is increasingly sought after for creating novel bioactive molecules with improved metabolic stability and target selectivity. This compound is primarily needed by research institutions and pharmaceutical companies engaged in the synthesis of new chemical entities, particularly for central nervous system (CNS) and oncology targets.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel active pharmaceutical ingredients (APIs), especially for neurological and psychiatric disorders.
• Medicinal Chemistry Research: Used extensively in hit-to-lead and lead optimization campaigns to explore structure-activity relationships (SAR).
• Ligand Synthesis: Employed in the development of receptor ligands and enzyme inhibitors due to its constrained, three-dimensional geometry.
• Chemical Biology Probes: Serves as a core scaffold for creating tool compounds to study biological pathways and target validation.
• Process Chemistry Development: Utilized in scaling up synthetic routes for preclinical and clinical candidate molecules.
• Library Synthesis: A valuable reactant for generating diverse compound libraries for high-throughput screening (HTS).

Basic Information

Product Name	2-Benzyl-2,6-Diazaspiro[3.3]Heptane Hydrochloride
CAS No.	1194375-85-3
Molecular Formula	C14H19N2Cl
Molecular Weight	250.77 g/mol
Synonyms	2-Benzyl-2,6-diazaspiro[3.3]heptane HCl; 2,6-Diazaspiro[3.3]heptane, 2-benzyl-, hydrochloride; 2-Benzyl-2,6-diazaspiro[3.3]heptane hydrochloride; 2-Benzyl-2,6-diazaspiro[3.3]heptane monohydrochloride; 2-Benzyl-2,6-diazaspiro[3.3]heptane HCl salt; 2-Benzyl-2,6-diazaspiro[3.3]heptane chloride; 2-Benzyl-2,6-diazaspiro[3.3]heptane, hydrochloride (1:1); 2-Benzyl-2,6-diazaspiro[3.3]heptane hydrochloride salt
EINECS	Contact for details

Quality Control

Our 2-Benzyl-2,6-Diazaspiro[3.3]Heptane Hydrochloride is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our commitment to quality supports compliance with cGMP and ICH guidelines for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept in a desiccated environment to prevent moisture absorption, which may affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.