Description

tert-Butyl 3,3A,4,5-Tetrahydro-1H-Pyrrolo[3,4-C]Quinoline-2(9Bh)-Carboxylate is a high-purity, advanced pharmaceutical intermediate crucial for the synthesis of complex bioactive molecules. Its value lies in its role as a key building block for constructing fused heterocyclic scaffolds found in modern drug discovery programs. This compound is essential for research and development chemists in the pharmaceutical and biotechnology sectors, particularly those focused on central nervous system (CNS) and oncology targets.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the multi-step synthesis of novel drug candidates, especially those containing complex polycyclic frameworks.
• Medicinal Chemistry Research: Used as a versatile scaffold for constructing libraries of compounds for high-throughput screening (HTS) and structure-activity relationship (SAR) studies.
• API Development: Employed in the research and process development stages for active pharmaceutical ingredients (APIs) targeting neurological disorders.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process optimization for client projects.
• Academic Research: Utilized in university and institutional labs for methodological development in organic synthesis and heterocyclic chemistry.
• Pre-clinical Development: Integral to the synthesis of compounds for pharmacological evaluation and toxicology studies.

Basic Information

Item	Details
Product Name	tert-Butyl 3,3A,4,5-Tetrahydro-1H-Pyrrolo[3,4-C]Quinoline-2(9Bh)-Carboxylate
CAS No.	1194375-23-9
Molecular Formula	C16H20N2O2
Molecular Weight	272.34 g/mol
Synonyms	tert-Butyl 2,3,3a,4-tetrahydro-1H-pyrrolo[3,4-c]quinoline-9b(2H)-carboxylate; 1,2,3,3a,4,9b-Hexahydropyrrolo[3,4-c]quinoline-2-carboxylic acid tert-butyl ester; 9bH-Pyrrolo[3,4-c]quinoline-2-carboxylic acid, 1,2,3,3a,4,9b-hexahydro-, 1,1-dimethylethyl ester; BOC-protected tetrahydro-pyrroloquinoline; tert-Butyl hexahydropyrrolo[3,4-c]quinoline-2(1H)-carboxylate
EINECS	Contact for details

Quality Control

Our tert-Butyl 3,3A,4,5-Tetrahydro-1H-Pyrrolo[3,4-C]Quinoline-2(9Bh)-Carboxylate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and available upon request. We support development needs with custom purity grades and can provide material suitable for GLP or pre-GMP applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.