Description

2-Bromo-5-Methylthiazole-4-Carboxylic Acid is a high-value heterocyclic building block and key synthetic intermediate. This compound matters for its role in constructing complex molecular architectures, particularly in the development of novel active pharmaceutical ingredients (APIs) and advanced agrochemicals. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for lead optimization and scale-up synthesis.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of potential drug candidates, especially those targeting central nervous system (CNS) disorders, anti-infectives, and metabolic diseases.
• Agrochemical Synthesis: Used in the research and development of new-generation herbicides, fungicides, and insecticides, leveraging the thiazole core's bioactivity.
• Material Science Research: Serves as a building block for creating novel organic ligands, functionalized polymers, and advanced organic electronic materials.
• Chemical Biology & Proteomics: Employed in the design and synthesis of chemical probes, activity-based probes (ABPs), and molecular tags for studying biological systems.
• Custom Synthesis & Contract Manufacturing: A key starting material for custom synthesis projects and contract manufacturing organizations (CMOs) producing specialized fine chemicals.

Basic Information

Product Name	2-Bromo-5-Methylthiazole-4-Carboxylic Acid
CAS No.	1194374-25-8
Molecular Formula	C6H4BrNO2S
Molecular Weight	222.07 g/mol
Synonyms	2-Bromo-5-methyl-1,3-thiazole-4-carboxylic acid; 4-Carboxy-2-bromo-5-methylthiazole; 5-Methyl-2-bromothiazole-4-carboxylic acid; 2-Bromo-5-methyl-4-thiazolecarboxylic acid; 2-Bromo-5-methylthiazole-4-carboxylate; 1194374-25-8; 2-Bromo-5-methyl-1,3-thiazole-4-carboxylate
EINECS	Contact for details

Quality Control

Our 2-Bromo-5-Methylthiazole-4-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for your most demanding R&D and scale-up projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to minimize exposure to moisture. Store away from incompatible materials such as strong bases and strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.