Description

1-(But-3-Yn-1-Yl)Piperazine Dihydrochloride is a high-purity, functionalized piperazine derivative of significant interest in advanced organic synthesis. This compound serves as a critical versatile building block for constructing complex molecular architectures, particularly in pharmaceutical research and development. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon for the development of new drug candidates, particularly in medicinal chemistry programs targeting CNS disorders, oncology, and infectious diseases.
• Agrochemical Synthesis: Used in the research and production of novel pesticides, herbicides, and plant growth regulators, leveraging its piperazine core for biological activity.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Chemical Biology Probes: Employed in the synthesis of molecular probes and tags for studying biological processes and target engagement.
• Polymer Modification: The alkyne functionality allows for click chemistry reactions, enabling the modification of polymers and surfaces for advanced material science applications.
• Custom Synthesis and Contract Manufacturing: A valuable starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the global life sciences market.

Basic Information

Product Name	1-(But-3-Yn-1-Yl)Piperazine Dihydrochloride
CAS No.	1193389-48-8
Molecular Formula	C8H16Cl2N2
Molecular Weight	211.13 g/mol
Synonyms	1-(But-3-yn-1-yl)piperazine dihydrochloride; 1-(3-Butynyl)piperazine dihydrochloride; 4-(But-3-yn-1-yl)piperazine-1,1-diium dichloride; Piperazine, 1-(3-butyn-1-yl)-, dihydrochloride; But-3-yn-1-yl-piperazine dihydrochloride; N-(But-3-ynyl)piperazine dihydrochloride
EINECS	Contact for details

Quality Control

Our 1-(But-3-Yn-1-Yl)Piperazine Dihydrochloride is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity, NMR for structural confirmation, and KF titration for water content, to ensure it meets the stringent requirements of research and development. Certificates of Analysis (COA) with full traceability are provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.