Description

(2,3-Dihydro-1,4-Benzodioxin-6-Ylmethyl)(2,2,2-Trifluoroethyl)Amine Hydrochloride is a high-purity, synthetically valuable organic compound, primarily utilized as a key intermediate in advanced pharmaceutical research and development. Its core value proposition lies in enabling the synthesis of novel therapeutic agents, particularly those targeting the central nervous system. This compound is essential for medicinal chemists and process development scientists in the pharmaceutical and biotechnology industries who require reliable, high-quality building blocks for drug discovery programs.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of novel drug candidates, particularly for central nervous system (CNS) targets.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization processes to develop new therapeutic molecules.
• Process Chemistry Development: Serves as a key starting material or intermediate for scaling up synthetic routes under Good Manufacturing Practice (GMP) conditions.
• Bioconjugation & Probe Synthesis: Potential use in creating labeled compounds or molecular probes for biochemical and pharmacological assays.
• Agrochemical Research: May be investigated as an intermediate for developing new active ingredients in crop protection science.
• Academic & Contract Research: Supplied to universities and CROs (Contract Research Organizations) for fundamental organic synthesis and drug discovery projects.

Basic Information

Product Name	(2,3-Dihydro-1,4-Benzodioxin-6-Ylmethyl)(2,2,2-Trifluoroethyl)Amine Hydrochloride
CAS No.	1193388-47-4
Molecular Formula	C12H14F3NO2•HCl
Molecular Weight	297.70 g/mol
Synonyms	6-[[(2,2,2-Trifluoroethyl)amino]methyl]-2,3-dihydro-1,4-benzodioxine hydrochloride; 1,4-Benzodioxin-6-methanamine, N-(2,2,2-trifluoroethyl)-, hydrochloride (1:1); (2,3-Dihydro-1,4-benzodioxin-6-ylmethyl)(2,2,2-trifluoroethyl)amine HCl; (6-((2,2,2-Trifluoroethylamino)methyl)-2,3-dihydrobenzo[b][1,4]dioxine hydrochloride); 2,3-Dihydro-1,4-benzodioxin-6-ylmethyl(2,2,2-trifluoroethyl)amine hydrochloride
EINECS	Contact for details

Quality Control

Our (2,3-Dihydro-1,4-Benzodioxin-6-Ylmethyl)(2,2,2-Trifluoroethyl)Amine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the high standards required for pharmaceutical research. Certificates of Analysis (COA) with detailed chromatographic data are available for every shipment. We support development projects requiring compliance with ICH guidelines and can provide material suitable for use under cGMP for Phase I-III clinical trials upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) when not in use to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure (1H & 19F NMR)
Assay (HPLC)	≥ 98.0%
Purity (HPLC)	≥ 99.0% (Total area %)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.