Description

4-Fluoro-n-(Thiophen-2-Ylmethyl)Aniline Hydrochloride is a high-purity organic building block and pharmaceutical intermediate. This compound is valued for its unique molecular architecture, which incorporates both a fluorinated aniline moiety and a thiophene heterocycle, enabling precise modifications in advanced chemical synthesis. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, agrochemical, and material science industries for developing novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly in medicinal chemistry programs targeting CNS disorders and oncology.
• Agrochemical Synthesis: Used in the creation of advanced pesticides and herbicides, where the fluorine atom and heterocyclic structure can enhance biological activity and environmental stability.
• Material Science Research: Serves as a precursor for organic electronic materials, such as semiconductors and conductive polymers, due to the electron-rich thiophene unit.
• Chemical Biology Probes: Employed in the design of fluorescent tags and molecular probes for studying biological processes and enzyme interactions.
• Academic & R&D Laboratories: A versatile building block for methodological development in organic synthesis and catalysis studies.
• Custom Synthesis & Contract Manufacturing: A critical starting material for the production of bespoke fine chemicals and complex target molecules under cGMP or ISO standards.

Basic Information

Product Name	4-Fluoro-n-(Thiophen-2-Ylmethyl)Aniline Hydrochloride
CAS No.	1193388-02-1
Molecular Formula	C11H11ClFNS
Molecular Weight	243.73 g/mol
Synonyms	N-[(Thiophen-2-yl)methyl]-4-fluoroaniline hydrochloride; 4-Fluoro-N-(thiophen-2-ylmethyl)benzenamine hydrochloride; 1-(4-Fluorophenyl)-N-(thiophen-2-ylmethyl)methanimine hydrochloride; 4-Fluoro-N-(2-thienylmethyl)aniline HCl; 4-Fluoro-N-(thiophen-2-ylmethyl)phenylamine hydrochloride; Benzenamine, 4-fluoro-N-(2-thienylmethyl)-, hydrochloride; 1193388-02-1
EINECS	Contact for details

Quality Control

Our 4-Fluoro-n-(Thiophen-2-Ylmethyl)Aniline Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to ISO 9001 principles, and we support development under cGMP guidelines for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment. Keep away from strong acids, strong bases, and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.