Description

R-3-Methylphenylglycine Hydrochloride is a high-purity chiral amino acid derivative essential for advanced pharmaceutical synthesis. This compound serves as a critical building block in the development of active pharmaceutical ingredients (APIs), particularly for its role in creating enantiomerically pure molecules. It is primarily utilized by research institutions and manufacturers in the pharmaceutical and fine chemical industries engaged in peptide synthesis and the production of novel therapeutics.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of complex APIs and investigational new drugs.
• Peptide Chemistry: Used as a protected amino acid derivative in solid-phase and solution-phase peptide synthesis.
• Asymmetric Synthesis: Employed as a starting material or auxiliary in catalytic asymmetric reactions to induce chirality.
• Biochemical Research: Serves as a standard or reagent in metabolic pathway studies and enzyme inhibition research.
• Fine Chemical Production: Integral to the manufacture of specialty chemicals, agrochemicals, and advanced material precursors.

Basic Information

Product Name	R-3-Methylphenylglycine Hydrochloride
CAS No.	1192552-00-3
Molecular Formula	C9H12ClNO2
Molecular Weight	201.65 g/mol
Synonyms	(R)-2-Amino-2-(3-methylphenyl)acetic acid hydrochloride; (R)-3-Methylphenylglycine HCl; D-3-Methylphenylglycine hydrochloride; (R)-α-Amino-3-methylbenzeneacetic acid hydrochloride; (2R)-2-Amino-2-(3-methylphenyl)ethanoic acid hydrochloride; (R)-2-Amino-2-(m-tolyl)acetic acid hydrochloride; UNII-7Q2Y2F4J6R
EINECS	Contact for details

Quality Control

Our R-3-Methylphenylglycine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis for enantiomeric excess, and identity confirmation via IR and NMR spectroscopy. Certificates of Analysis (COA) detailing all specifications are provided to ensure traceability and compliance with your research or cGMP guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Enantiomeric Purity (Chiral HPLC)	≥99.0% ee
Loss on Drying	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.