Description

{[(1R,2R)-2-Amino-1,2-Diphenylethyl](4-Toluenesulfonyl)Amido}(p-Cymene)(Pyridine)Ruthenium(II)Tetrafluoroborate is a highly specialized organometallic complex featuring a chiral diamine ligand, designed for advanced catalytic applications. This compound is valued for its role as a precise and efficient catalyst in asymmetric synthesis, enabling the production of enantiomerically pure compounds. It is primarily sought after by research institutions and pharmaceutical manufacturers engaged in the development of active pharmaceutical ingredients (APIs), fine chemicals, and novel materials.

Application

• Asymmetric Hydrogenation: A key catalyst for the enantioselective reduction of prochiral ketones, olefins, and imines to produce chiral alcohols and amines.
• Pharmaceutical Intermediate Synthesis: Enables the creation of stereochemically defined building blocks for Active Pharmaceutical Ingredients (APIs) and drug candidates.
• Fine Chemical Production: Used in the synthesis of high-value, optically pure compounds for agrochemicals, flavors, and fragrances.
• Academic & Industrial Research: Serves as a critical reagent in methodological development for new catalytic transformations and mechanistic studies.
• Chiral Ligand Screening: Acts as a precursor or benchmark catalyst in the discovery and optimization of new chiral catalyst systems.

Basic Information

Product Name	{[(1R,2R)-2-Amino-1,2-Diphenylethyl](4-Toluenesulfonyl)Amido}(p-Cymene)(Pyridine)Ruthenium(II)Tetrafluoroborate
CAS No.	1192483-15-0
Molecular Formula	C35H38BF4N3ORuS
Molecular Weight	722.62 g/mol
Synonyms	Ru-TsDPEN-(p-cymene) Tetrafluoroborate; (R,R)-TsDPEN-Ru(II)-(p-cymene) BF4; N-[(1R,2R)-2-Amino-1,2-diphenylethyl]-4-methylbenzenesulfonamido-(p-cymene)-pyridine-ruthenium(II) tetrafluoroborate; Ruthenium(II) (p-cymene) (pyridine) (N-tosyl-1,2-diphenylethylenediamine) tetrafluoroborate; Asymmetric Hydrogenation Catalyst (Ru-TsDPEN type); [RuCl(p-cymene)(TsDPEN)]BF4 analog; Chiral Ruthenium Diamine Catalyst
EINECS	Contact for details

Quality Control

Our {[(1R,2R)-2-Amino-1,2-Diphenylethyl](4-Toluenesulfonyl)Amido}(p-Cymene)(Pyridine)Ruthenium(II)Tetrafluoroborate is manufactured under strict quality protocols to ensure batch-to-batch consistency and high catalytic performance. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and chiral integrity. We adhere to relevant cGMP guidelines for advanced chemical intermediates to support our clients' regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when opening to prevent decomposition. For long-term stability, consider storage at 2-8°C.

Specification

Item	Specification
Appearance	Orange to red crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Meets ICH guidelines
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.