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{[(1R,2R)-2-Amino-1,2-Diphenylethyl](4-Toluenesulfonyl)Amido}(p-Cymene)(Pyridine)Ruthenium(Ii) Tetrafluoroborate, Min. 97% CAS NO 1192483-14-9


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CAS No.:1192483-14-9

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

{[(1R,2R)-2-Amino-1,2-Diphenylethyl](4-Toluenesulfonyl)Amido}(p-Cymene)(Pyridine)Ruthenium(II) Tetrafluoroborate, Min. 97% is a high-purity, chiral ruthenium complex designed for advanced asymmetric synthesis. This compound matters as a highly efficient and selective catalyst, enabling critical carbon-carbon and carbon-heteroatom bond-forming reactions under mild conditions. It is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries who require precise stereochemical control for synthesizing complex, high-value molecules.

Application

  • Asymmetric Hydrogenation: A key catalyst for the enantioselective reduction of ketones, imines, and olefins to produce chiral alcohols, amines, and other intermediates.
  • Pharmaceutical Intermediate Synthesis: Enables the production of single-enantiomer active pharmaceutical ingredients (APIs) for drugs targeting CNS disorders, cardiovascular diseases, and infectious diseases.
  • Agrochemical Manufacturing: Used in the synthesis of chiral herbicides, fungicides, and plant growth regulators where biological activity is stereospecific.
  • Academic & Industrial R&D: A valuable tool for methodology development and exploring new catalytic transformations in organic chemistry laboratories.
  • Fine Chemical Production: Facilitates the manufacture of chiral flavors, fragrances, and advanced materials with specific optical properties.
  • Transfer Hydrogenation Reactions: Effective in reactions using alternative hydrogen donors like isopropanol or formic acid for safer and more convenient processes.

Basic Information

Product Name {[(1R,2R)-2-Amino-1,2-Diphenylethyl](4-Toluenesulfonyl)Amido}(p-Cymene)(Pyridine)Ruthenium(II) Tetrafluoroborate, Min. 97%
CAS No. 1192483-14-9
Molecular Formula C35H38BF4N3ORuS
Molecular Weight 722.62 g/mol
Synonyms Ru-TsDPEN(p-cymene) Tetrafluoroborate; (R,R)-TsDPEN-Ru(II)(p-cymene) Complex; N-[(1R,2R)-2-Amino-1,2-diphenylethyl]-4-methylbenzenesulfonamido-(p-cymene)pyridineruthenium(II) Tetrafluoroborate; Ruthenium(II) (R,R)-TsDPEN (p-cymene) Catalyst; Asymmetric Hydrogenation Catalyst Ru-TsDPEN; [RuCl(p-cymene)(TsDPEN)]BF4; (R,R)-N-(p-Toluenesulfonyl)-1,2-diphenylethylenediamine Ruthenium Complex; (R,R)-Ru-TsDPEN(p-cymene)BF4
EINECS Contact for details

Quality Control

Our ruthenium catalyst is manufactured under strict quality protocols to ensure batch-to-batch consistency and optimal catalytic performance. Each lot undergoes comprehensive analysis, including chiral purity verification and residual metal screening. Certificates of Analysis (COA) detailing assay, enantiomeric excess, and impurity profiles are provided to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., argon or nitrogen) at 2-8°C in a cool, dry place. This compound is hygroscopic (moisture-sensitive) and easily oxidized; prolonged exposure to air, moisture, or elevated temperatures will degrade its catalytic activity.

Specification

Item Specification
Appearance Orange to red crystalline powder
Identification (IR) Conforms to structure
Assay (HPLC) Min. 97.0%
Chiral Purity (HPLC) Min. 99.0% e.e.
Solubility Soluble in dichloromethane, acetone; slightly soluble in methanol
Residual Solvents (GC) Meets ICH guidelines
Heavy Metals < 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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