Description

2-(6-(Trifluoromethyl)Pyridin-2-Yl)Propan-2-Amine Hydrochloride is a high-purity, advanced pharmaceutical intermediate featuring a trifluoromethylpyridine core, a privileged scaffold in modern drug discovery. This compound is valued for its role in modulating the physicochemical and metabolic properties of active pharmaceutical ingredients (APIs), particularly in enhancing lipophilicity and metabolic stability. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of novel therapeutics, including kinase inhibitors and central nervous system (CNS) agents.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of small molecule drugs, especially kinase inhibitors and other targeted therapies.
• Agrochemical Research: Used in the development of advanced pesticides and herbicides, where the trifluoromethyl group can improve biological activity and environmental stability.
• Chemical Biology & Proteomics: Serves as a versatile scaffold for creating chemical probes and tool compounds to study biological pathways and protein function.
• Material Science Precursor: Potential use in the synthesis of specialty chemicals and functional materials, such as ligands for catalysts or monomers for advanced polymers.
• Contract Research & Development (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for the life sciences industry.

Basic Information

Product Name	2-(6-(Trifluoromethyl)Pyridin-2-Yl)Propan-2-Amine Hydrochloride
CAS No.	1192356-27-6
Molecular Formula	C9H10ClF3N2
Molecular Weight	238.64 g/mol
Synonyms	2-(6-(Trifluoromethyl)pyridin-2-yl)propan-2-amine hydrochloride; 2-Propan-2-amine, 2-[6-(trifluoromethyl)pyridin-2-yl]-, hydrochloride; 2-Amino-2-[6-(trifluoromethyl)-2-pyridyl]propane hydrochloride; 2-(6-(Trifluoromethyl)-2-pyridinyl)-2-propylamine hydrochloride; 1-(6-(Trifluoromethyl)pyridin-2-yl)ethan-1-amine hydrochloride (tautomeric form); TFMPA-HCl; 2-(6-TFM-Pyridin-2-yl)isopropylamine HCl
EINECS	Contact for details

Quality Control

Our 2-(6-(Trifluoromethyl)Pyridin-2-Yl)Propan-2-Amine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.