Description

3-Bromo-2-Chloro-5-Methyl[1,6]Naphthyridine is a high-purity, multi-functional heterocyclic building block of significant interest in advanced organic synthesis. Its core value lies in its unique halogenated naphthyridine scaffold, which provides versatile reactivity for constructing complex molecular architectures. This compound is essential for researchers and process chemists in the pharmaceutical and agrochemical industries, particularly for developing novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, especially kinase inhibitors and other biologically active heterocycles.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides due to its bioactive core structure.
• Material Science: Serves as a building block for creating organic electronic materials, such as ligands for metal-organic frameworks (MOFs) or components for organic semiconductors.
• Chemical Synthesis: Utilized in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and nucleophilic substitution reactions to introduce complex functionalities.
• Academic & R&D: A valuable reagent for methodological studies and exploring new chemical spaces in university and corporate research laboratories.

Basic Information

Product Name	3-Bromo-2-Chloro-5-Methyl[1,6]Naphthyridine
CAS No.	1192263-93-6
Molecular Formula	C9H6BrClN2
Molecular Weight	257.51 g/mol
Synonyms	3-Bromo-2-chloro-5-methyl-1,6-naphthyridine; 2-Chloro-3-bromo-5-methyl-1,6-naphthyridine; 5-Methyl-3-bromo-2-chloro[1,6]naphthyridine; [1,6]Naphthyridine, 3-bromo-2-chloro-5-methyl-; 1192263-93-6; 3-Br-2-Cl-5-Me-[1,6]naphthyridine
EINECS	Contact for details

Quality Control

Our 3-Bromo-2-Chloro-5-Methyl[1,6]Naphthyridine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide Certificates of Analysis (COA) with detailed specifications for trace metals, residual solvents, and related substances, supporting its use in regulated research and development environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound should be kept under an inert atmosphere if long-term stability is required and handled in accordance with good laboratory practices.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.