Description

1-(2,5-Difluorophenyl)Ethanamine Hydrochloride is a high-purity organic building block and pharmaceutical intermediate of significant commercial interest. This compound is valued for its role in the synthesis of more complex molecules, particularly in medicinal chemistry and advanced material science. It is primarily sought by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for developing novel active ingredients.

Application

• Pharmaceutical Intermediate: A key chiral building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in drug discovery programs targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides, leveraging the difluorophenyl moiety for enhanced biological activity and metabolic stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Chemical Research: Employed in academic and industrial R&D for exploring new organic reactions and synthesizing complex molecular architectures for material science applications.
• Fine Chemical Production: An essential raw material in the multi-step synthesis of dyes, pigments, and other high-value specialty chemicals.

Basic Information

Product Name	1-(2,5-Difluorophenyl)Ethanamine Hydrochloride
CAS No.	1191908-45-8
Molecular Formula	C8H10ClF2N
Molecular Weight	193.62 g/mol
Synonyms	1-(2,5-Difluorophenyl)ethan-1-amine hydrochloride; α-Methyl-2,5-difluorobenzeneethanamine hydrochloride; (1-(2,5-Difluorophenyl)ethyl)amine hydrochloride; 2,5-Difluoro-α-methylbenzylamine hydrochloride; 1-(2,5-Difluorophenyl)ethylamine HCl; 2,5-Difluoroamphetamine hydrochloride (research context); (R/S)-1-(2,5-Difluorophenyl)ethanamine hydrochloride
EINECS	Contact for details

Quality Control

Our 1-(2,5-Difluorophenyl)Ethanamine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and identity confirmation. A Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.