Description

3A-(Trifluoromethyl)-2,3,3A,4-Tetrahydro-1H-Benzo[D]Pyrrolo[1,2-A]Imidazol-1-One is a high-value, fluorinated heterocyclic compound, identified by CAS No. 1191278-87-1, serving as a critical building block in advanced organic synthesis. Its core value lies in the unique reactivity and physicochemical properties imparted by the trifluoromethyl group and the fused benzimidazolone scaffold, enabling the development of novel molecules with enhanced metabolic stability and bioavailability. This compound is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for creating new active ingredients, as well as by fine chemical manufacturers specializing in custom synthesis.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of new drug candidates, particularly in oncology, CNS disorders, and anti-infective therapies.
• Agrochemical Synthesis: Used in the design and synthesis of novel herbicides, fungicides, and insecticides, where the fluorine atoms can improve lipophilicity and biological activity.
• Material Science Research: Serves as a precursor for developing specialty polymers, liquid crystals, or organic electronic materials due to its rigid, fused-ring structure.
• Chemical Biology Probe Development: Employed in the construction of molecular probes and inhibitors for studying enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: Supplied to fine chemical companies for use in bespoke, multi-step synthesis projects for clients.
• Academic & Institutional Research: Utilized in university and government laboratories for fundamental studies in synthetic methodology and fluorine chemistry.

Basic Information

Product Name	3A-(Trifluoromethyl)-2,3,3A,4-Tetrahydro-1H-Benzo[D]Pyrrolo[1,2-A]Imidazol-1-One
CAS No.	1191278-87-1
Molecular Formula	C12H10F3N3O
Molecular Weight	269.22 g/mol
Synonyms	3a-(Trifluoromethyl)-1,2,3,3a,4,8b-hexahydropyrrolo[1,2-a]benzimidazol-1-one; 3a-(Trifluoromethyl)-2,3,3a,4-tetrahydro-1H-benzo[d]pyrrolo[1,2-a]imidazol-1-one; 3a-(Trifluoromethyl)-2,3,3a,4-tetrahydro-1H-pyrrolo[1,2-a]benzimidazol-1-one; 1H-Benzo[d]pyrrolo[1,2-a]imidazol-1-one, 2,3,3a,4-tetrahydro-3a-(trifluoromethyl)-; Pyrrolo[1,2-a]benzimidazol-1-one, 2,3,3a,4-tetrahydro-3a-(trifluoromethyl)-; 1191278-87-1
EINECS	Contact for details

Quality Control

Our production of 3A-(Trifluoromethyl)-2,3,3A,4-Tetrahydro-1H-Benzo[D]Pyrrolo[1,2-A]Imidazol-1-One adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis by GC. We provide detailed Certificates of Analysis (COA) with each shipment, ensuring traceability and compliance with your research or manufacturing standards. Our quality system is designed to support cGMP and ISO guidelines for advanced pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its chemical nature, keep away from incompatible materials such as strong bases and fluorides. For long-term storage, consider inert atmosphere conditions to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.