Description

1-Boc-4-Hydroxy-4-(3-Pyridinyl)-Piperidine CAS NO 1191240-34-2 is a high-purity, advanced pharmaceutical intermediate featuring a piperidine core substituted with both a tert-butoxycarbonyl (Boc) protecting group and a 3-pyridinyl moiety. This compound is critical for medicinal chemistry research and development, serving as a versatile building block for the synthesis of complex bioactive molecules. It is primarily utilized by pharmaceutical R&D teams and fine chemical manufacturers engaged in developing new therapeutic agents, particularly in the areas of central nervous system (CNS) and oncology drug discovery.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the multi-step synthesis of novel active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Used as a scaffold for structure-activity relationship (SAR) studies to optimize drug potency and selectivity.
• Protecting Group Strategy: The Boc group allows for selective manipulation of the piperidine nitrogen during complex synthetic sequences.
• Ligand and Probe Development: Serves as a starting material for creating chemical probes and ligands targeting biological receptors.
• Process Chemistry & Scale-Up: Employed in the development and optimization of scalable synthetic routes for candidate drugs.

Basic Information

Product Name	1-Boc-4-Hydroxy-4-(3-Pyridinyl)-Piperidine
CAS No.	1191240-34-2
Molecular Formula	C15H22N2O3
Molecular Weight	278.35 g/mol
Synonyms	1-Boc-4-(3-Pyridyl)-4-hydroxypiperidine; tert-Butyl 4-hydroxy-4-(pyridin-3-yl)piperidine-1-carboxylate; 4-Hydroxy-4-(3-pyridinyl)-1-piperidinecarboxylic acid 1,1-dimethylethyl ester; 1-(tert-Butoxycarbonyl)-4-hydroxy-4-(3-pyridyl)piperidine; 4-(Pyridin-3-yl)-4-hydroxypiperidine-1-carboxylic acid tert-butyl ester; 1-Boc-4-(3-pyridinyl)-4-piperidinol; 4-Hydroxy-4-(3-pyridinyl)piperidine-1-carboxylic acid tert-butyl ester
EINECS	Contact for details

Quality Control

Our 1-Boc-4-Hydroxy-4-(3-Pyridinyl)-Piperidine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and structural identity. Certificates of Analysis (COA) detailing purity, impurities, and physical characteristics are provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.