Description

Tricyclohexylphosphine[4,5-Dimethyl-1,3-Bis(2,4,6-Trimethylphenyl)Imidazol-2-Ylidene][2-Thienylmethylene] Ruthenium(Ii) Dichloride, Min. 95% is a highly specialized, second-generation Grubbs-Hoveyda type olefin metathesis catalyst. This compound is engineered for superior thermal stability and functional group tolerance, enabling efficient and selective carbon-carbon double bond formation in complex molecular architectures. It is an essential reagent for R&D and production chemists in the pharmaceutical, agrochemical, and advanced materials sectors, where precision and reliability in catalytic transformations are paramount.

Application

• Pharmaceutical Intermediate Synthesis: Key catalyst for ring-closing metathesis (RCM), cross metathesis (CM), and ring-opening metathesis polymerization (ROMP) in the production of active pharmaceutical ingredients (APIs) and complex heterocycles.
• Agrochemical Development: Used in the synthesis of novel herbicides, fungicides, and insecticides that require the construction of specific olefin frameworks.
• Polymer & Material Science: Enables the synthesis of specialty polymers, functionalized materials, and self-healing polymers via ROMP and acyclic diene metathesis (ADMET) polymerization.
• Fine Chemical Production: Facilitates the efficient, large-scale synthesis of fragrance compounds, specialty olefins, and other high-value fine chemicals.
• Academic & Industrial R&D: A critical tool for methodology development and exploring new synthetic routes in organic chemistry laboratories worldwide.
• Petrochemical Refining: Applied in catalytic processes for the modification of olefin streams and the synthesis of higher-value petrochemical derivatives.

Basic Information

Product Name	Tricyclohexylphosphine[4,5-Dimethyl-1,3-Bis(2,4,6-Trimethylphenyl)Imidazol-2-Ylidene][2-Thienylmethylene] Ruthenium(II) Dichloride, Min. 95%
CAS No.	1190427-50-9
Molecular Formula	C48H66Cl2N2PRuS
Molecular Weight	~912.04 g/mol
Synonyms	Grubbs-Hoveyda II Catalyst; Hoveyda-Grubbs Catalyst 2nd Generation; (1,3-Bis(2,4,6-trimethylphenyl)-4,5-dimethylimidazol-2-ylidene)(2-thienylmethylene)(tricyclohexylphosphine)ruthenium(II) dichloride; HG II Catalyst; Zhan Catalyst 1B; [RuCl2(IMesH2)(CH-2-Thienyl)(PCy3)]; Dichloro[1,3-bis(2,4,6-trimethylphenyl)-4,5-dimethyl-2-imidazolidinylidene][2-(2-thienyl)methylidene](tricyclohexylphosphine)ruthenium
EINECS	Contact for details

Quality Control

Our Tricyclohexylphosphine[4,5-Dimethyl-1,3-Bis(2,4,6-Trimethylphenyl)Imidazol-2-Ylidene][2-Thienylmethylene] Ruthenium(II) Dichloride is manufactured under stringent quality management systems. Every batch undergoes rigorous analytical testing, including NMR (1H, 13C, 31P) and HPLC analysis, to confirm identity, purity, and catalytic activity. A comprehensive Certificate of Analysis (COA) detailing assay, impurity profile, and residual solvent content is provided with each shipment to ensure traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store the product under an inert atmosphere (argon or nitrogen) at 2-8°C. The compound is easily oxidized and moisture-sensitive; therefore, containers should be opened only in a controlled, dry environment and resealed immediately after use. Allow the sealed container to equilibrate to room temperature before opening to prevent condensation.

Specification

Item	Specification
Appearance	Purple to brown crystalline solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	Min. 95%
Solubility	Soluble in common organic solvents (DCM, toluene, THF)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.