Description

4-(Trifluoromethyl)-7-Azaindole-3-Carboxylic Acid is a high-value heterocyclic building block featuring a fused azaindole core with both a carboxylic acid and a trifluoromethyl group. This unique structure makes it a critical intermediate for the synthesis of novel pharmaceuticals and agrochemicals, where it imparts desirable properties like metabolic stability and enhanced binding affinity. It is primarily sought after by research and development teams in the pharmaceutical, biotechnology, and agrochemical sectors for drug discovery programs and the development of advanced active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of kinase inhibitors, receptor antagonists, and other small-molecule therapeutics.
• Agrochemical Research: Used in developing new herbicides, fungicides, and insecticides with improved efficacy and environmental profiles.
• Chemical Biology: Serves as a versatile scaffold for creating probes and tool compounds to study biological pathways.
• Material Science: Potential precursor for advanced organic electronic materials due to its electron-deficient azaindole system.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development.

Basic Information

Product Name	4-(Trifluoromethyl)-7-Azaindole-3-Carboxylic Acid
CAS No.	1190320-72-9
Molecular Formula	C9H5F3N2O2
Molecular Weight	230.15 g/mol
Synonyms	7-Azaindole-3-carboxylic acid, 4-(trifluoromethyl)-; 4-(Trifluoromethyl)-1H-pyrrolo[2,3-b]pyridine-3-carboxylic acid; 1H-Pyrrolo[2,3-b]pyridine-3-carboxylic acid, 4-(trifluoromethyl)-; 4-Trifluoromethyl-7-azaindole-3-carboxylic acid
EINECS	Contact for details

Quality Control

Our 4-(Trifluoromethyl)-7-Azaindole-3-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our quality commitment supports applications requiring high-purity intermediates for research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This compound is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept sealed and away from direct light sources to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.