Description

3-Bromo-7-(Trifluoromethyl)-4-Azaindole is a high-value, multi-functional heterocyclic building block designed for advanced chemical synthesis. This compound matters because it combines a reactive bromine substituent with a stable trifluoromethyl group and a 4-azaindole core, offering a unique scaffold for structure-activity relationship (SAR) studies and molecular diversification. It is primarily needed by medicinal chemistry and agrochemical research teams for the development of novel pharmaceuticals and crop protection agents, where its distinct pharmacophore is critical for modulating biological activity and physicochemical properties.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of kinase inhibitors, receptor antagonists, and other small-molecule drug candidates.
• Agrochemical Research: Serves as a core structure for creating novel herbicides, fungicides, and insecticides with enhanced efficacy and selectivity.
• Chemical Biology Probe: Used in the design and synthesis of molecular probes to study enzyme function and biological pathways.
• Material Science Precursor: Potential building block for advanced organic electronic materials and functional polymers.
• Cross-Coupling Reactions: The bromine atom makes it an excellent substrate for Suzuki, Stille, and Buchwald-Hartwig amination reactions to create complex molecular architectures.
• Library Synthesis: Employed in parallel and combinatorial chemistry for generating diverse compound libraries for high-throughput screening.

Basic Information

Product Name	3-Bromo-7-(Trifluoromethyl)-4-Azaindole
CAS No.	1190320-45-6
Molecular Formula	C8H4BrF3N2
Molecular Weight	265.04 g/mol
Synonyms	3-Bromo-7-(trifluoromethyl)-1H-pyrrolo[2,3-b]pyridine; 7-(Trifluoromethyl)-3-bromo-1H-pyrrolo[2,3-b]pyridine; 3-Bromo-7-trifluoromethyl-4-aza-indole; 3-Bromo-7-trifluoromethyl-1H-pyrrolo[2,3-b]pyridine; 1H-Pyrrolo[2,3-b]pyridine, 3-bromo-7-(trifluoromethyl)-; 3-Bromo-7-(trifluoromethyl)-1H-pyrrolo[2,3-b]pyridine
EINECS	Contact for details

Quality Control

Our 3-Bromo-7-(Trifluoromethyl)-4-Azaindole is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our commitment to cGMP principles and adherence to ISO standards ensure reliable supply for your most demanding research and development projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound is moisture-sensitive; keep the container tightly sealed under an inert atmosphere to prevent degradation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Impurity (HPLC)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.