Description

4-Fluoro-3-Iodo-7-Azaindole is a high-value halogenated heterocyclic building block, specifically a functionalized 7-azaindole derivative. This compound is engineered to serve as a critical intermediate in modern pharmaceutical and agrochemical research, enabling the synthesis of novel bioactive molecules. It is primarily sought after by R&D chemists and process development scientists in the life sciences sector for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key synthon for the development of kinase inhibitors, anticancer agents, and other small-molecule therapeutics targeting protein-protein interactions.
• Agrochemical Research: Used in the synthesis of novel herbicides, fungicides, and plant growth regulators that leverage its unique halogenated azaindole scaffold.
• Material Science Precursor: Serves as a building block for organic electronic materials, such as organic light-emitting diodes (OLEDs) and semiconductors, due to its electron-deficient heterocyclic core.
• Cross-Coupling Reactions: The iodine and fluorine substituents make it an excellent substrate for versatile palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Sonogashira, Buchwald-Hartwig).
• Medicinal Chemistry SAR Studies: Enables structure-activity relationship (SAR) exploration by allowing selective functionalization at multiple positions on the azaindole ring system.
• Chemical Biology Probes: Utilized in the design and synthesis of chemical probes for target identification and validation in biological systems.

Basic Information

Product Name	4-Fluoro-3-Iodo-7-Azaindole
CAS No.	1190320-05-8
Molecular Formula	C7H4FIN2
Molecular Weight	277.02 g/mol
Synonyms	3-Iodo-4-fluoro-1H-pyrrolo[2,3-b]pyridine; 4-Fluoro-3-iodo-1H-pyrrolo[2,3-b]pyridine; 1H-Pyrrolo[2,3-b]pyridine, 4-fluoro-3-iodo-; 4-Fluoro-3-iodo-7-aza-indole; 3-Iodo-4-fluoro-7-azaindole; 4-Fluoro-3-iodo-1H-7-azaindole; 7-Azaindole, 4-fluoro-3-iodo-
EINECS	Contact for details

Quality Control

Our 4-Fluoro-3-Iodo-7-Azaindole is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity for research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP principles where applicable to support our clients' regulatory and quality assurance requirements from discovery through development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound is light-sensitive; prolonged exposure to light should be avoided to maintain stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.