Description

4-Chloro-5-Aza-2-Oxindole is a high-purity, heterocyclic organic compound serving as a critical synthetic intermediate. Its value lies in its unique molecular scaffold, which is essential for constructing complex pharmacologically active molecules. This product is primarily needed by research institutions and pharmaceutical companies engaged in the development of novel therapeutic agents and advanced organic synthesis.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of kinase inhibitors and other targeted small-molecule drug candidates.
• Medicinal Chemistry Research: Used extensively in lead optimization and structure-activity relationship (SAR) studies for new chemical entities.
• Organic Synthesis: Serves as a versatile precursor for constructing complex heterocyclic frameworks and fused ring systems.
• Biochemical Tool Compound: Potential use in developing probes for studying specific biological pathways and enzyme functions.
• Contract Manufacturing: Supplied to CDMOs for use in custom synthesis and scale-up projects under cGMP conditions.

Basic Information

Product Name	4-Chloro-5-Aza-2-Oxindole
CAS No.	1190313-48-4
Molecular Formula	C7H4ClN3O
Molecular Weight	181.58 g/mol
Synonyms	4-Chloro-1,5-dihydro-2H-pyrrolo[3,2-b]pyridin-2-one; 4-Chloro-5-azaoxindole; 4-Chloro-5-aza-2-oxindole; 1,5-Dihydro-4-chloro-2H-pyrrolo[3,2-b]pyridin-2-one; 4-Chloro-1H-pyrrolo[3,2-b]pyridin-2(5H)-one; 4-Chloro-5-azaindolin-2-one; CAS 1190313-48-4
EINECS	Contact for details

Quality Control

Our 4-Chloro-5-Aza-2-Oxindole is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept in a desiccated environment to prevent moisture uptake, which may affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.