Description

3-Nitro-6-Azaindole-7-Carboxylic Acid is a high-purity, advanced pharmaceutical intermediate characterized by its unique heterocyclic structure. This compound is critical for medicinal chemistry research and development, serving as a versatile building block for synthesizing novel drug candidates. It is primarily sought after by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in developing targeted therapies, particularly in oncology and antiviral domains.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex small-molecule drugs targeting specific biological pathways.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Kinase Inhibitor Development: Employed in the construction of potential kinase inhibitors due to the azaindole moiety's affinity for ATP-binding sites.
• Chemical Biology Probes: Utilized to create tool compounds for studying enzyme function and cellular signaling processes.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations providing custom synthesis and process development services.
• Academic Research: Used in university and institutional labs for exploratory synthetic chemistry and bioorganic research projects.

Basic Information

Product Name	3-Nitro-6-Azaindole-7-Carboxylic Acid
CAS No.	1190310-03-2
Molecular Formula	C8H5N3O4
Molecular Weight	207.14 g/mol
Synonyms	7-Carboxy-3-nitro-1H-pyrrolo[2,3-b]pyridine; 3-Nitro-1H-pyrrolo[2,3-b]pyridine-7-carboxylic acid; 3-Nitro-7-carboxy-6-azaindole; 1H-Pyrrolo[2,3-b]pyridine-7-carboxylic acid, 3-nitro-; 3-Nitro-6-aza-1H-indole-7-carboxylic acid; 3-Nitro-6-azaindole-7-carboxylic acid methyl ester (precursor); 6-Azaindole-7-carboxylic acid, 3-nitro- derivative
EINECS	Contact for details

Quality Control

Our 3-Nitro-6-Azaindole-7-Carboxylic Acid is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC for purity and NMR/LC-MS for identity confirmation, to ensure it meets the exacting standards required for pharmaceutical research. Certificates of Analysis (COA) with detailed chromatographic data are provided and available upon request to support your regulatory and quality documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	Yellow to brown powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms to reference spectrum
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.