Description

3-(3-Chloro-4-Methoxyphenyl)-7-(Thiomorpholin-4-Ylcarbonyl)Quinazolin-4(3H)-One is a sophisticated quinazolinone derivative, a key chemical scaffold in modern pharmaceutical research and development. This compound matters for its role as a crucial pharmaceutical intermediate or active pharmaceutical ingredient (API) building block, enabling the synthesis of targeted therapeutic agents. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, biotechnology, and fine chemical industries focused on developing novel small-molecule drugs.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of potential kinase inhibitors and other targeted therapeutic agents.
• Oncology Research: Used in the discovery and development of novel anti-cancer compounds, leveraging the quinazolinone core's biological activity.
• Biochemical Tool Compound: Employed in vitro and in vivo studies to investigate specific biological pathways and validate drug targets.
• Process Chemistry & Scale-Up: Utilized in route scouting, optimization, and pilot-scale production for new chemical entities (NCEs).
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthesis projects.
• Academic Research: Provides a specialized substrate for universities and research institutes studying heterocyclic chemistry and medicinal chemistry.

Basic Information

Product Name	3-(3-Chloro-4-Methoxyphenyl)-7-(Thiomorpholin-4-Ylcarbonyl)Quinazolin-4(3H)-One
CAS No.	1190261-99-4
Molecular Formula	C21H19ClN4O3S
Molecular Weight	442.92 g/mol
Synonyms	7-[(Thiomorpholin-4-yl)carbonyl]-3-(3-chloro-4-methoxyphenyl)quinazolin-4(3H)-one; 3-(3-Chloro-4-methoxyphenyl)-7-(thiomorpholine-4-carbonyl)quinazolin-4(3H)-one; 1190261-99-4; UNII-9J8F8Q2A6V; 9J8F8Q2A6V; Quinazolin-4(3H)-one, 3-(3-chloro-4-methoxyphenyl)-7-(4-thiomorpholinylcarbonyl)-; AKOS025243065.
EINECS	Contact for details

Quality Control

Our 3-(3-Chloro-4-Methoxyphenyl)-7-(Thiomorpholin-4-Ylcarbonyl)Quinazolin-4(3H)-One is produced under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our commitment to quality supports compliance with cGMP standards where applicable for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.