Description

4-(1,4-Diazepan-1-Yl)-2-(Trifluoromethyl)-Quinazoline is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is valued for its role as a key building block in the research and development of novel therapeutic agents, particularly in medicinal chemistry. It is primarily sought by R&D laboratories and pharmaceutical manufacturers engaged in the synthesis of innovative drug candidates.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of active pharmaceutical ingredients (APIs) targeting various disease pathways.
• Medicinal Chemistry Research: Used as a scaffold or building block for designing and optimizing new chemical entities in drug discovery programs.
• Kinase Inhibitor Development: The quinazoline core is a privileged structure in the development of kinase inhibitors for oncology and other therapeutic areas.
• Chemical Biology Probes: Utilized in the creation of specialized probes for studying biological processes and target validation.
• Custom Synthesis: Employed in contract research and manufacturing (CRO/CMO) for bespoke synthesis projects requiring high-complexity intermediates.

Basic Information

Product Name	4-(1,4-Diazepan-1-Yl)-2-(Trifluoromethyl)-Quinazoline
CAS No.	1190198-38-9
Molecular Formula	C15H16F3N5
Molecular Weight	323.32 g/mol
Synonyms	2-(Trifluoromethyl)-4-(1,4-diazepan-1-yl)quinazoline; 4-(1,4-Diazepan-1-yl)-2-(trifluoromethyl)quinazoline; Quinazoline, 4-(1,4-diazepan-1-yl)-2-(trifluoromethyl)-; 1190198-38-9; 4-(1,4-Diazepan-1-yl)-2-(trifluoromethyl)quinazoline; 2-Trifluoromethyl-4-(1,4-diazepan-1-yl)quinazoline
EINECS	Contact for details

Quality Control

Our 4-(1,4-Diazepan-1-Yl)-2-(Trifluoromethyl)-Quinazoline is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). The product should be kept under an inert atmosphere for long-term storage to ensure stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.