Description

6-Bromo-8-Nitroquinolin-4(1H)-One is a high-purity, advanced pharmaceutical intermediate and versatile heterocyclic building block. This compound is critical for the synthesis of complex molecules, particularly in medicinal chemistry and materials science research. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel active compounds.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel quinoline-based drug candidates, including potential kinase inhibitors and antimicrobial agents.
• Agrochemical Research: Building block for developing new crop protection agents and herbicides due to its bioactive quinoline core.
• Organic Synthesis Reagent: Used in cross-coupling reactions, such as Suzuki or Buchwald-Hartwig amination, to introduce functionalized quinoline scaffolds.
• Material Science: Serves as a starting material for creating organic semiconductors, ligands for metal-organic frameworks (MOFs), and fluorescent dyes.
• Academic & Industrial R&D: Essential for method development and exploring new chemical spaces in heterocyclic chemistry.

Basic Information

Product Name	6-Bromo-8-Nitroquinolin-4(1H)-One
CAS No.	1190198-29-8
Molecular Formula	C9H5BrN2O3
Molecular Weight	269.06 g/mol
Synonyms	6-Bromo-8-nitro-1,4-dihydroquinolin-4-one; 6-Bromo-8-nitro-4-quinolinol; 4(1H)-Quinolinone, 6-bromo-8-nitro-; 6-Bromo-8-nitroquinolin-4-ol; 8-Nitro-6-bromoquinolin-4(1H)-one; 6-Bromo-8-nitro-4-hydroxyquinoline
EINECS	Contact for details

Quality Control

Our 6-Bromo-8-Nitroquinolin-4(1H)-One is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR/IR for structural confirmation, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed chromatographic data are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials. Due to its light-sensitive nature, handling should be performed under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.