Description

1,8-Naphthyridine-2-Carboxylic Acid Monohydrate is a heterocyclic carboxylic acid derivative that serves as a versatile and high-value building block in advanced organic synthesis. Its core value lies in its rigid bicyclic structure and functional groups, which are critical for constructing complex molecules with specific biological and material properties. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries, particularly for developing active pharmaceutical ingredients (APIs) and functional ligands.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting infectious diseases, neurological disorders, and oncology.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging its heterocyclic scaffold for bioactivity.
• Coordination Chemistry & Catalysis: Acts as a chelating ligand for metal ions, useful in creating catalysts for organic transformations and in materials science.
• Material Science: Employed in the synthesis of organic semiconductors, fluorescent dyes, and other functional organic materials.
• Academic & R&D: Serves as a fundamental research chemical for studying heterocyclic chemistry and reaction mechanisms.

Basic Information

Product Name	1,8-Naphthyridine-2-Carboxylic Acid Monohydrate
CAS No.	1189993-99-4
Molecular Formula	C9H8N2O3
Molecular Weight	192.17 g/mol (Monohydrate)
Synonyms	1,8-Naphthyridine-2-carboxylic acid hydrate; 2-Carboxy-1,8-naphthyridine monohydrate; 1,8-Naphthyridine-2-carboxylic acid, monohydrate; 1,8-Naphthyridin-2-carboxylic Acid Hydrate; 1,8-Naphthyridine-2-Carboxylic Acid (Hydrate)
EINECS	Contact for details

Quality Control

Our 1,8-Naphthyridine-2-Carboxylic Acid Monohydrate is produced under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for research and commercial synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to guarantee traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	7.0 - 9.5% (Theoretical for monohydrate: ~9.4%)
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.