Description

2-[4-(Trifluoromethyl)Phenoxy]Benzylamine Hcl is a high-purity organic intermediate featuring a trifluoromethylphenoxy-benzylamine core structure. This compound is valued for its role as a critical building block in the synthesis of advanced pharmaceutical agents and agrochemicals, where the trifluoromethyl group is known to enhance metabolic stability and bioavailability. It is primarily sought by R&D chemists and process development teams in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring fluorinated compounds.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl group improves efficacy.
• Ligand & Catalyst Development: Serves as a precursor for creating specialized ligands and catalysts used in asymmetric synthesis and cross-coupling reactions.
• Material Science Research: Employed in the synthesis of fluorinated polymers and advanced organic materials with unique properties.
• Bioconjugation & Probe Chemistry: The amine hydrochloride group allows for use in bioconjugation strategies to create fluorescent probes or targeted biomolecules.

Basic Information

Product Name	2-[4-(Trifluoromethyl)Phenoxy]Benzylamine Hcl
CAS No.	1189940-77-9
Molecular Formula	C14H11ClF3NO
Molecular Weight	301.69 g/mol
Synonyms	1-[[4-(Trifluoromethyl)phenoxy]methyl]benzenamine hydrochloride; 2-((4-(Trifluoromethyl)phenoxy)methyl)aniline hydrochloride; Benzenamine, 2-[[[4-(trifluoromethyl)phenyl]oxy]methyl]-, hydrochloride; α-(4-Trifluoromethylphenoxy)-o-toluidine hydrochloride; 2-[(4-Trifluoromethylphenoxy)methyl]phenylamine hydrochloride; (2-Aminobenzyl) 4-(trifluoromethyl) phenyl ether hydrochloride
EINECS	Contact for details

Quality Control

Our 2-[4-(Trifluoromethyl)Phenoxy]Benzylamine Hcl is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and heavy metals, to ensure it meets the stringent requirements for pharmaceutical and agrochemical R&D. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%, Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.