Description

2-(Quinolin-5-Ylamino)-1,3-Thiazole-4-Carboxylic Acid is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound matters as a critical building block in modern medicinal chemistry, enabling the synthesis of novel drug candidates with targeted biological activity. It is primarily needed by research institutions and pharmaceutical companies engaged in the development of new therapeutic agents, particularly in oncology and anti-infective research.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel small-molecule drug candidates targeting specific enzymes or receptors.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization programs due to its quinoline-thiazole hybrid scaffold.
• Chemical Biology Probes: Serves as a core structure for developing molecular probes to study biological pathways and protein functions.
• Organic Synthesis Building Block: Utilized in complex multi-step syntheses to introduce specific functional groups and heterocyclic motifs.
• Contract Research & Development (CRO): Supplied to CROs and CDMOs for client-specific custom synthesis projects.

Basic Information

Product Name	2-(Quinolin-5-Ylamino)-1,3-Thiazole-4-Carboxylic Acid
CAS No.	1189749-55-0
Molecular Formula	C₁₃H₉N₃O₂S
Molecular Weight	271.29 g/mol
Synonyms	2-[(Quinolin-5-yl)amino]-1,3-thiazole-4-carboxylic acid; 2-(Quinolin-5-ylamino)thiazole-4-carboxylic acid; 5-Quinolylaminothiazole-4-carboxylic acid; 2-(5-Quinolylamino)-4-thiazolecarboxylic acid; 1189749-55-0; Quinolin-5-ylamino-thiazolecarboxylic acid; 2-(Quinolin-5-ylamino)-1,3-thiazole-4-carboxylic acid
EINECS	Contact for details

Quality Control

Our 2-(Quinolin-5-Ylamino)-1,3-Thiazole-4-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR/LC-MS for structural confirmation, to ensure it meets the high standards required for pharmaceutical research. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.