Description

1-Benzhydrylpiperidine-4-Carboxylic Acid HCl is a high-purity organic building block and pharmaceutical intermediate of significant commercial interest. Its unique benzhydryl-piperidine scaffold makes it a valuable precursor in medicinal chemistry research and development. This compound is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and fine chemical industries for the synthesis of novel active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and other therapeutic areas.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization programs due to its versatile piperidine-carboxylic acid core.
• Chemical Synthesis: Serves as a precursor for creating more complex molecules, including potential receptor ligands and enzyme inhibitors.
• Fine Chemical Production: Employed in the multi-step synthesis of specialty chemicals and advanced materials.
• Reference Standard: Can be supplied as a high-purity standard for analytical method development and quality control in API manufacturing.

Basic Information

Product Name	1-Benzhydrylpiperidine-4-Carboxylic Acid HCl
CAS No.	1189689-68-6
Molecular Formula	C19H21NO2·HCl
Molecular Weight	331.84 g/mol (Free base: 295.38 g/mol)
Synonyms	4-(Diphenylmethyl)-1-piperidinecarboxylic acid hydrochloride; 1-(Diphenylmethyl)-4-piperidinecarboxylic acid hydrochloride; Benzhydryl-4-piperidinecarboxylic acid HCl; 1-(Benzhydryl)piperidine-4-carboxylic acid hydrochloride; 4-Carboxy-1-benzhydrylpiperidine hydrochloride; Piperidine-4-carboxylic acid, 1-(diphenylmethyl)-, hydrochloride; 1189689-68-6
EINECS	Contact for details

Quality Control

Our 1-Benzhydrylpiperidine-4-Carboxylic Acid HCl is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, to ensure it meets the high standards required for pharmaceutical research and development. A Certificate of Analysis (COA) detailing identity, purity, and related substances is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.