Description

2-[3,5-Bis(Trifluoromethyl)Phenyl]-2-Phenylethylamine HCl is a high-purity, fluorinated amine hydrochloride salt, a key building block in advanced organic synthesis. This compound is valued for its unique trifluoromethylated aromatic structure, which imparts desirable properties like enhanced metabolic stability and lipophilicity to target molecules. It is primarily utilized by research and development chemists in the pharmaceutical and agrochemical industries for the creation of novel active ingredients.

Application

• Pharmaceutical Intermediate: A critical chiral building block for the synthesis of potential drug candidates, particularly in central nervous system (CNS) and oncology research.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, where the trifluoromethyl groups can improve biological activity and environmental stability.
• Ligand & Catalyst Development: Serves as a precursor for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of fluorinated polymers and advanced organic electronic materials.
• Chemical Biology Probes: Useful for creating tagged molecules to study biological pathways and protein interactions.
• Custom Synthesis & Scale-Up: Supplied for contract research organizations (CROs) and CDMOs for process development and non-GMP/ GMP production.

Basic Information

Product Name	2-[3,5-Bis(Trifluoromethyl)Phenyl]-2-Phenylethylamine HCl
CAS No.	1189486-71-2
Molecular Formula	C16H13ClF6N
Molecular Weight	368.73 g/mol
Synonyms	2-[3,5-Bis(trifluoromethyl)phenyl]-2-phenylethan-1-amine hydrochloride; 1-[3,5-Bis(trifluoromethyl)phenyl]-2-phenylethylamine hydrochloride; α-Methyl-3,5-bis(trifluoromethyl)benzenepropanamine hydrochloride; (RS)-2-[3,5-Bis(trifluoromethyl)phenyl]-2-phenylethylamine HCl; 2-Phenyl-2-[3,5-bis(trifluoromethyl)phenyl]ethylamine hydrochloride; 2-(3,5-Bis(trifluoromethyl)phenyl)-2-phenylethylamine HCl; 1-Phenyl-2-[3,5-bis(trifluoromethyl)phenyl]ethylamine hydrochloride
EINECS	Contact for details

Quality Control

Our 2-[3,5-Bis(Trifluoromethyl)Phenyl]-2-Phenylethylamine HCl is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identity confirmation via NMR and MS, to ensure it meets the stringent requirements for research and development. Certificates of Analysis (COA) with detailed chromatographic data are provided for full traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which can affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	Contact for details
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.