Description

1,3-Dihydro-2-benzofuran-5-sulfonamide is a high-purity, advanced pharmaceutical intermediate and versatile organic building block. Its core value lies in its unique benzofuran-sulfonamide scaffold, which is a privileged structure in medicinal chemistry for designing bioactive molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly those developing novel enzyme inhibitors and receptor modulators.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates targeting various therapeutic areas.
• Medicinal Chemistry Research: Used as a core scaffold for constructing libraries of compounds in high-throughput screening and structure-activity relationship (SAR) studies.
• Enzyme Inhibitor Development: The sulfonamide group makes it a valuable starting point for designing potent inhibitors of carbonic anhydrases and other metalloenzymes.
• Agrochemical Synthesis: Serves as a building block for developing new herbicides, fungicides, or plant growth regulators with enhanced efficacy.
• Chemical Biology Probes: Utilized in the creation of molecular probes to study biological pathways and protein functions.
• Material Science: Potential monomer or additive for creating specialized polymers with specific electronic or optical properties.

Basic Information

Product Name	1,3-Dihydro-2-benzofuran-5-sulfonamide
CAS No.	1189378-81-1
Molecular Formula	C8H9NO3S
Molecular Weight	199.23 g/mol
Synonyms	5-Sulfamoyl-2,3-dihydro-1-benzofuran; 2,3-Dihydrobenzofuran-5-sulfonamide; 1-Benzofuran-5-sulfonamide, 2,3-dihydro-; 2,3-Dihydro-1-benzofuran-5-sulfonic acid amide; Dihydrobenzofuransulfonamide; Benzofuran-5-sulfonamide, 2,3-dihydro-; 1189378-81-1
EINECS	Contact for details

Quality Control

Our 1,3-Dihydro-2-benzofuran-5-sulfonamide is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from strong oxidizing agents. For long-term storage under an inert atmosphere, please contact our technical team for specific recommendations.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.